SCOPe 2.07: Domain d4gacb_: 4gac B:

Lineage for d4gacb_ (4gac B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein automated matches [190169] (7 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [187524] (12 PDB entries)

8. Domain d4gacb_: 4gac B: [194360]
   automated match to d2alra_
   complexed with edo, flc

Details for d4gacb_

PDB Entry: 4gac, 1.64 Å

PDB Description: high resolution structure of mouse aldehyde reductase (akr1a4) in its apo-form

PDB Compounds: (B:) Alcohol dehydrogenase [NADP(+)]

SCOPe Domain Sequences for d4gacb_:

Sequence, based on SEQRES records:

>d4gacb_ c.1.7.1 (B:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
assvllhtgqkmpliglgtwksepgqvkaaikhalsagyrhidcasvygneteigealke
svgsgkavpreelfvtsklwntkhhpedvepalrktladlqleyldlylmhwpyafergd
npfpknadgtvrydsthyketwkalevlvakglvkalglsnfnsrqiddvlsvasvrpav
lqvechpylaqneliahcharglevtaysplgssdrawrhpdepvlleepvvlalaekhg
rspaqillrwqvqrkvicipksinpsrilqniqvfdftfspeemkqldalnknwryivpm
itvdgkrvprdaghplypfndpy

Sequence, based on observed residues (ATOM records):

>d4gacb_ c.1.7.1 (B:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
assvllhtgqkmpliglgtwksepgqvkaaikhalsagyrhidcasvygneteigealke
svgsgkavpreelfvtsklwntkhhpedvepalrktladlqleyldlylmhwpyafergd
npfpkgtvrydsthyketwkalevlvakglvkalglsnfnsrqiddvlsvasvrpavlqv
echpylaqneliahcharglevtaysplgpdepvlleepvvlalaekhgrspaqillrwq
vqrkvicipksinpsrilqniqvfdftfspeemkqldalnknwryivpmvprdaghplyp
fndpy

Timeline for d4gacb_:

• d4gacb_ first appeared in SCOPe 2.02
  
• d4gacb_ appears in SCOPe 2.06
  
• d4gacb_ appears in the current release, SCOPe 2.08