SCOPe 2.04: Domain d1siga_: 1sig A:

Lineage for d1siga_ (1sig A:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.177: Sigma2 domain of RNA polymerase sigma factors [88945] (1 superfamily)
   multihelical; consists of a conserved 4-helical core and a variable insert subdomain

4. Superfamily a.177.1: Sigma2 domain of RNA polymerase sigma factors [88946] (2 families)

5. Family a.177.1.1: Sigma2 domain of RNA polymerase sigma factors [88947] (6 proteins)

6. Protein Sigma70 [88948] (2 species)

7. Species Escherichia coli [TaxId:562] [48332] (1 PDB entry)

8. Domain d1siga_: 1sig A: [19068]
   sigma2 domain only with a large insert subdomain

Details for d1siga_

PDB Entry: 1sig, 2.6 Å

PDB Description: crystal structure of a sigma70 subunit fragment from escherichia coli rna polymerase

PDB Compounds: (A:) RNA polymerase primary sigma factor

SCOPe Domain Sequences for d1siga_:

Sequence, based on SEQRES records:

>d1siga_ a.177.1.1 (A:) Sigma70 {Escherichia coli [TaxId: 562]}
megeidiakriedginqvqcsvaeypeaitylleqynrveaeearlsdlitgfvdpnaee
dlaptathvgselsqedldddededeedgdddsadddnsidpelarekfaelraqyvvtr
dtikakgrshataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcv
eqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetg
ltieqvkdinrrmsigeakarrakkemveanlrlvisiakkytnrglqfldliqegnigl
mkavdkfeyrrgykfstyatwwirqaitrsiadq

Sequence, based on observed residues (ATOM records):

>d1siga_ a.177.1.1 (A:) Sigma70 {Escherichia coli [TaxId: 562]}
megeidiakriedginqvqcsvaeypeaitylleqynrveaeearlsdlitgfvddlapt
athvgselsqedldidpelarekfaelraqyvvtrdtikahataqeeilklsevfkqfrl
vpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaia
mnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemve
anlrlvisiakkytnrglqfldliqegniglmkavdkfeyrrgykfstyatwwirqaitr
siadq

Timeline for d1siga_:

• d1siga_ first appeared (with stable ids) in SCOP 1.55, called d1sig__
  
• d1siga_ appears in SCOPe 2.03
  
• d1siga_ appears in SCOPe 2.05
  
• d1siga_ appears in the current release, SCOPe 2.08, called d1siga1