SCOPe 2.08: Domain d3gr6j1: 3gr6 J:1-256

Lineage for d3gr6j1 (3gr6 J:1-256)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein Enoyl-ACP reductase [51791] (11 species)

7. Species Staphylococcus aureus [TaxId:1280] [189086] (3 PDB entries)

8. Domain d3gr6j1: 3gr6 J:1-256 [176928]
   Other proteins in same PDB: d3gr6d2, d3gr6j2
   automated match to d1ulua_
   complexed with nap, tcl

Details for d3gr6j1

PDB Entry: 3gr6, 2.28 Å

PDB Description: Crystal structure of the staphylococcus aureus enoyl-acyl carrier protein reductase (fabI) in complex with NADP and triclosan

PDB Compounds: (J:) Enoyl-[acyl-carrier-protein] reductase [NADH]

SCOPe Domain Sequences for d3gr6j1:

Sequence; same for both SEQRES and ATOM records:

>d3gr6j1 c.2.1.2 (J:1-256) Enoyl-ACP reductase {Staphylococcus aureus [TaxId: 1280]}
mlnlenktyvimgiankrsiafgvakvldqlgaklvftyrkersrkeleklleqlnqpea
hlyqidvqsdeevingfeqigkdvgnidgvyhsiafanmedlrgrfsetsregfllaqdi
ssysltivaheakklmpeggsivattylggefavqnynvmgvakasleanvkylaldlgp
dnirvnaisagpirtlsakgvggfntilkeieeraplkrnvdqvevgktaayllsdlssg
vtgenihvdsgfhaik

Timeline for d3gr6j1:

• d3gr6j1 first appeared in SCOPe 2.01, called d3gr6j_
  
• d3gr6j1 appears in SCOPe 2.07