SCOPe 2.08: Domain d3cldb_: 3cld B:

Lineage for d3cldb_ (3cld B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Glucocorticoid receptor [89140] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89141] (8 PDB entries)

8. Domain d3cldb_: 3cld B: [173314]
   automated match to d1m2za_
   protein/DNA complex; complexed with gw6

Details for d3cldb_

PDB Entry: 3cld, 2.84 Å

PDB Description: ligand binding domain of the glucocorticoid receptor complexed with fluticazone furoate

PDB Compounds: (B:) Glucocorticoid receptor

SCOPe Domain Sequences for d3cldb_:

Sequence, based on SEQRES records:

>d3cldb_ a.123.1.1 (B:) Glucocorticoid receptor {Human (Homo sapiens) [TaxId: 9606]}
ltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgfrnl
hlddqmtllqyswmylmafalgwrsyrqssanllcfapdliineqrmtlpgmydqckhml
yvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivkregn
ssqnwqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysng
nikkllfhq

Sequence, based on observed residues (ATOM records):

>d3cldb_ a.123.1.1 (B:) Glucocorticoid receptor {Human (Homo sapiens) [TaxId: 9606]}
ltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgfrnl
hlddqmtllqyswmylmafalgwrsyrqnllcfapdliineqrmtlpgmydqckhmlyvs
selhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivkrqnwqrf
yqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysngnikkllfh
q

Timeline for d3cldb_:

• d3cldb_ first appeared in SCOPe 2.01
  
• d3cldb_ appears in SCOPe 2.07