SCOPe 2.07: Domain d4fapb_: 4fap B:

Lineage for d4fapb_ (4fap B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family)
   automatically mapped to Pfam PF08771

5. Family a.24.7.1: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47213] (2 proteins)

6. Protein mTOR FKBP12–rapamycin-binding (FRB) domain [47214] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47215] (11 PDB entries)

8. Domain d4fapb_: 4fap B: [16617]
   Other proteins in same PDB: d4fapa_
   complexed with ard

Details for d4fapb_

PDB Entry: 4fap, 2.8 Å

PDB Description: atomic structures of the rapamycin analogs in complex with both human fkbp12 and frb domain of frap

PDB Compounds: (B:) fkbp12-rapamycin associated protein

SCOPe Domain Sequences for d4fapb_:

Sequence; same for both SEQRES and ATOM records:

>d4fapb_ a.24.7.1 (B:) mTOR FKBP12–rapamycin-binding (FRB) domain {Human (Homo sapiens) [TaxId: 9606]}
vailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdl
meaqewcrkymksgnvkdltqawdlyyhvfrris

Timeline for d4fapb_:

• d4fapb_ first appeared (with stable ids) in SCOP 1.55
  
• d4fapb_ appears in SCOPe 2.06
  
• d4fapb_ appears in the current release, SCOPe 2.08