Lineage for d3b2ra2 (3b2r A:535-860)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2014835Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2014836Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2014926Family a.211.1.2: PDEase [48548] (7 protein domains)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 2015121Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species)
  7. 2015122Species Human (Homo sapiens) [TaxId:9606] [101440] (19 PDB entries)
    Uniprot O76074 534-860
  8. 2015135Domain d3b2ra2: 3b2r A:535-860 [154768]
    Other proteins in same PDB: d3b2ra3
    automated match to d1rkpa_
    complexed with vdn

Details for d3b2ra2

PDB Entry: 3b2r (more details), 2.07 Å

PDB Description: Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
PDB Compounds: (A:) cGMP-specific 3',5'-cyclic phosphodiesterase

SCOPe Domain Sequences for d3b2ra2:

Sequence, based on SEQRES records: (download)

>d3b2ra2 a.211.1.2 (A:535-860) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens) [TaxId: 9606]}
eetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhev
lcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshd
ldhrgvnnsyiqrsehplaqlychsimehhhfdqclmilnspgnqilsglsieeykttlk
iikqailatdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpi
qqriaelvateffdqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyealth
vsedcfplldgcrknrqkwqalaeqq

Sequence, based on observed residues (ATOM records): (download)

>d3b2ra2 a.211.1.2 (A:535-860) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens) [TaxId: 9606]}
eetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhev
lcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshd
ldhrgvchsimehhhfdqclmilnspgnqilsglsieeykttlkiikqailatdlalyik
rrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqqriaelvateffdqg
dkknkipsmqvgfidaiclqlyealthvsedcfplldgcrknrqkwqalaeqq

SCOPe Domain Coordinates for d3b2ra2:

Click to download the PDB-style file with coordinates for d3b2ra2.
(The format of our PDB-style files is described here.)

Timeline for d3b2ra2:

View in 3D
Domains from same chain:
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d3b2ra3
View in 3D
Domains from other chains:
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d3b2rb_