SCOPe 2.03: Domain d2hyec3: 2hye C:403-675

Lineage for d2hyec3 (2hye C:403-675)

1. Root: SCOPe 2.03

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.40: Cullin homology domain [75631] (1 superfamily)
   3 domains: (1) 4-helical bundle; (2) alpha+beta; (3) "winged helix"-like

4. Superfamily e.40.1: Cullin homology domain [75632] (1 family)

5. Family e.40.1.1: Cullin homology domain [75633] (2 proteins)

6. Protein Cullin-4A [160968] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [160969] (1 PDB entry)
   Uniprot Q13619 402-675

8. Domain d2hyec3: 2hye C:403-675 [145416]
   Other proteins in same PDB: d2hyec1, d2hyec2, d2hyed1
   complexed with zn

Details for d2hyec3

PDB Entry: 2hye, 3.1 Å

PDB Description: crystal structure of the ddb1-cul4a-rbx1-sv5v complex

PDB Compounds: (C:) Cullin-4A

SCOPe Domain Sequences for d2hyec3:

Sequence; same for both SEQRES and ATOM records:

>d2hyec3 e.40.1.1 (C:403-675) Cullin-4A {Human (Homo sapiens) [TaxId: 9606]}
nkpaeliakhvdsklragnkeatdeelertldkimilfrfihgkdvfeafykkdlakrll
vgksasvdaeksmlsklkhecgaaftsklegmfkdmelskdimvhfkqhmqnqsdsgpid
ltvniltmgywptytpmevhltpemiklqevfkafylgkhsgrklqwqttlghavlkaef
kegkkefqvslfqtlvllmfnegdgfsfeeikmatgiedselrrtlqslacgkarvliks
pkgkevedgdkfifngefkhklfrikinqiqmk

Timeline for d2hyec3:

• d2hyec3 first appeared in SCOP 1.75
  
• d2hyec3 appears in SCOPe 2.02
  
• d2hyec3 appears in SCOPe 2.04
  
• d2hyec3 appears in the current release, SCOPe 2.08