SCOPe 2.07: Protein: Endophilin-1

Root: SCOPe 2.07
Class a: All alpha proteins [46456] (289 folds)
Fold a.238: BAR/IMD domain-like [116747] (1 superfamily)
6 helices, homodimer of 3-helical domains
Superfamily a.238.1: BAR/IMD domain-like [103657] (5 families)
core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends
Family a.238.1.1: BAR domain [103658] (4 proteins)
sensor of membrane curvature
Protein Endophilin-1 [140699] (3 species)
SH3-containing GRB2-like protein 2

Human (Homo sapiens) [TaxId:9606] [140701] (3 PDB entries)
Uniprot Q99962 11-247! Uniprot Q99962 26-247
1. Domain for 1x03:
  - Domain d1x03a1: 1x03 A:26-247 [121541]
2. Domain for 1x04:
  - Domain d1x04a1: 1x04 A:26-225 [121542]
    mutant
3. Domain for 2d4c:
  - Domain d2d4ca1: 2d4c A:11-247 [131246]
    Other proteins in same PDB: d2d4cb_, d2d4cc_, d2d4cd_
    complexed with ca; mutant
Mouse (Mus musculus) [TaxId:10090] [140702] (1 PDB entry)
Uniprot Q62420 27-246
- Domains for 1zww:
  1. Domain d1zwwa1: 1zww A:27-246 [125750]
    complexed with cd
  2. Domain d1zwwb_: 1zww B: [125751]
    automated match to d2d4ca1
    complexed with cd
Norway rat (Rattus norvegicus) [TaxId:10116] [140700] (1 PDB entry)
Uniprot Q62420 25-247
UniProt sequence of Rat species, O35179, is a fragment that does not cover the entire domain
- Domain for 2c08:
  - Domain d2c08a1: 2c08 A:25-247 [129578]

Timeline for Protein Endophilin-1 from a.238.1.1: BAR domain:

Protein Endophilin-1 from a.238.1.1: BAR domain first appeared in SCOP 1.73
Protein Endophilin-1 from a.238.1.1: BAR domain appears in SCOPe 2.06
Protein Endophilin-1 from a.238.1.1: BAR domain appears in the current release, SCOPe 2.08