SCOPe 2.08: Domain d2nvxa1: 2nvx A:3-1445

Lineage for d2nvxa1 (2nvx A:3-1445)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.29: beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1 superfamily)
   Multidomain subunits of complex domain organization

4. Superfamily e.29.1: beta and beta-prime subunits of DNA dependent RNA-polymerase [64484] (3 families)
   The catalytic site is formed by the association of two double-psi beta-barrel domains, one from each subunit

5. Family e.29.1.2: RNA-polymerase beta-prime [64490] (4 proteins)

6. Protein RBP1 [64486] (2 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64487] (24 PDB entries)
   Uniprot P04050; part of multichain biological unit

8. Domain d2nvxa1: 2nvx A:3-1445 [138667]
   Other proteins in same PDB: d2nvxb1, d2nvxc1, d2nvxc2, d2nvxe1, d2nvxe2, d2nvxf1, d2nvxh1, d2nvxi1, d2nvxi2, d2nvxj1, d2nvxk1, d2nvxl1
   automatically matched to d1i50a_
   protein/DNA complex; protein/RNA complex; complexed with dut, mg, zn

Details for d2nvxa1

PDB Entry: 2nvx, 3.6 Å

PDB Description: RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP

PDB Compounds: (A:) DNA-directed RNA polymerase II largest subunit

SCOPe Domain Sequences for d2nvxa1:

Sequence, based on SEQRES records:

>d2nvxa1 e.29.1.2 (A:3-1445) RBP1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsid
rnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelm
rqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglklv
gswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvp
pppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvat
ymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnleld
qvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskrag
diqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspynadf
dgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtfie
ldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkd
ngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngf
stgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrfl
neardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdr
tlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlv
kaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdll
ntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirr
iiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccll
rsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmtln
tfhfagvaskkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaiehtt
lksvtiaseiyydpdprstvipedeeiiqlhfslldeeaeqsfdqqspwllrleldraam
ndkdltmgqvgerikqtfkndlfviwsedndekliircrvvrpksldaeteaeedhmlkk
ientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvpgi
dptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqgglt
svtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtgafd
vmi

Sequence, based on observed residues (ATOM records):

>d2nvxa1 e.29.1.2 (A:3-1445) RBP1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsid
rnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelm
rqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglklv
gswklrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvppppvrpsisfne
sqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvatymdndiagqpqa
lqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnleldqvgvpksiaktl
typevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskragdiqlqygwkver
himdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspynadfdgdemnlhvpqs
eetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtfieldqvlnmlywvp
dwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkdngmliidgqiif
gvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngfstgigdtiadgp
tmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrflneardkagrlae
vnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdrtlphfskddysp
eskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlvkaledimvhydn
ttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdllntdhtldpslle
sgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirriiqnaqqtfhid
htkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccllrsrlatrrvlqe
yrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmtlkkvtsgvprlkei
lnvaknmktpsltvylepghaadqeqaklirsaiehttlksvtiaseiyydpdprstvip
edeeiiqlhfslqqspwllrleldraamndkdltmgqvgerikqtfkndlfviwsednde
kliircrvvraeedhmlkkientmlenitlrgveniervvmmkydrkvpsptgeyvkepe
wvletdgvnlsevmtvpgidptriytnsfidimevlgieagraalykevynviasdgsyv
nyrhmallvdvmttqggltsvtrhgfnrsntgalmrcsfeetveilfeagasaelddcrg
vsenvilgqmapigtgafdvmi

Timeline for d2nvxa1:

• d2nvxa1 first appeared in SCOP 1.73
  
• d2nvxa1 appears in SCOPe 2.07