SCOPe 2.01: Domain d2ghuc1: 2ghu C:1-241

Lineage for d2ghuc1 (2ghu C:1-241)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (23 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein Falcipain 2 [142846] (1 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [142847] (4 PDB entries)
   Uniprot Q9N6S8 244-484

8. Domain d2ghuc1: 2ghu C:1-241 [135212]
   automatically matched to 1YVB A:0-212

Details for d2ghuc1

PDB Entry: 2ghu, 3.1 Å

PDB Description: Crystal structure of falcipain-2 from Plasmodium falciparum

PDB Compounds: (C:) falcipain 2

SCOPe Domain Sequences for d2ghuc1:

Sequence, based on SEQRES records:

>d2ghuc1 d.3.1.1 (C:1-241) Falcipain 2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
qmnyeevikkyrgeenfdhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairkn
klitlseqelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrct
ekygiknylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvg
fgmkeivnpltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafipli
e

Sequence, based on observed residues (ATOM records):

>d2ghuc1 d.3.1.1 (C:1-241) Falcipain 2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
qmnyeevikkyrgnfdhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairknkl
itlseqelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrctek
ygiknylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvgfg
mkeivnpltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafiplie

Timeline for d2ghuc1:

• d2ghuc1 first appeared in SCOP 1.73
  
• d2ghuc1 appears in SCOP 1.75
  
• d2ghuc1 appears in SCOPe 2.02
  
• d2ghuc1 appears in the current release, SCOPe 2.08, called d2ghuc_