SCOPe 2.08: Domain d2ghuc_: 2ghu C:

Lineage for d2ghuc_ (2ghu C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein Falcipain 2 [142846] (1 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [142847] (5 PDB entries)
   Uniprot Q9N6S8 244-484

8. Domain d2ghuc_: 2ghu C: [135212]
   automated match to d2oula_

Details for d2ghuc_

PDB Entry: 2ghu, 3.1 Å

PDB Description: Crystal structure of falcipain-2 from Plasmodium falciparum

PDB Compounds: (C:) falcipain 2

SCOPe Domain Sequences for d2ghuc_:

Sequence, based on SEQRES records:

>d2ghuc_ d.3.1.1 (C:) Falcipain 2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
qmnyeevikkyrgeenfdhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairkn
klitlseqelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrct
ekygiknylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvg
fgmkeivnpltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafipli
e

Sequence, based on observed residues (ATOM records):

>d2ghuc_ d.3.1.1 (C:) Falcipain 2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
qmnyeevikkyrgnfdhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairknkl
itlseqelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrctek
ygiknylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvgfg
mkeivnpltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafiplie

Timeline for d2ghuc_:

• d2ghuc_ first appeared in SCOP 1.73, called d2ghuc1
  
• d2ghuc_ appears in SCOPe 2.07