Lineage for d2g8ea2 (2g8e A:33-356)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2926589Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2926590Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2927079Family d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)
    automatically mapped to Pfam PF00648
  6. 2927080Protein Calpain large subunit, catalytic domain (domain II) [54041] (6 species)
    includes the N-terminal 'sequence' domain I
  7. 2927098Species Norway rat (Rattus norvegicus), mu-type [TaxId:10116] [75332] (10 PDB entries)
    Uniprot P97571 33-353
  8. 2927108Domain d2g8ea2: 2g8e A:33-356 [134769]
    Other proteins in same PDB: d2g8ea3
    automated match to d1tloa_
    complexed with 0m6, ca, mes

Details for d2g8ea2

PDB Entry: 2g8e (more details), 2.25 Å

PDB Description: calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
PDB Compounds: (A:) Calpain-1 catalytic subunit

SCOPe Domain Sequences for d2g8ea2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2g8ea2 d.3.1.3 (A:33-356) Calpain large subunit, catalytic domain (domain II) {Norway rat (Rattus norvegicus), mu-type [TaxId: 10116]}

SCOPe Domain Coordinates for d2g8ea2:

Click to download the PDB-style file with coordinates for d2g8ea2.
(The format of our PDB-style files is described here.)

Timeline for d2g8ea2:

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