Lineage for Protein: Calpain large subunit, catalytic domain (domain II)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2497139Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2497140Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2497603Family d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)
    automatically mapped to Pfam PF00648
  6. 2497604Protein Calpain large subunit, catalytic domain (domain II) [54041] (6 species)
    includes the N-terminal 'sequence' domain I

Species:

  1. 2497605Human (Homo sapiens) [TaxId:9606] [225239] (1 PDB entry)
  2. 2497608Human (Homo sapiens), calpain 9 [TaxId:9606] [142850] (1 PDB entry)
    Uniprot O14815 28-337
  3. 2497610Human (Homo sapiens), M-type [TaxId:9606] [54042] (2 PDB entries)
    1. Domain for 1kfu:
    2. Domain for 1kfx:
  4. 2497613Human (Homo sapiens), mu type [TaxId:9606] [142851] (2 PDB entries)
    Uniprot P07384 33-353! Uniprot P07384 33-354
    1. Domain for 1zcm:
    2. Domains for 2ary:
      1. 2497614Domain d2arya1: 2ary A:33-354 [127223]
        complexed with bme, ca
      2. 2497615Domain d2aryb_: 2ary B: [127224]
        automated match to d2arya1
        complexed with bme, ca
  5. 2497617Norway rat (Rattus norvegicus), M-type [TaxId:10116] [54043] (3 PDB entries)
    1. Domain for 1df0:
    2. Domains for 1mdw:
      1. 2497618Domain d1mdwa_: 1mdw A: [84934]
        calcium-bound protease core
        complexed with ca
      2. 2497619Domain d1mdwb_: 1mdw B: [84935]
        calcium-bound protease core
        complexed with ca
    3. Domain for 1u5i:
  6. 2497622Norway rat (Rattus norvegicus), mu-type [TaxId:10116] [75332] (10 PDB entries)
    Uniprot P97571 33-353
    1. Domains for 1kxr:
      1. 2497626Domain d1kxra_: 1kxr A: [73175]
        calcium-bound protease core
        complexed with ca
      2. 2497627Domain d1kxrb_: 1kxr B: [73176]
        calcium-bound protease core
        complexed with ca
    2. Domains for 1qxp:
      1. 2497633Domain d1qxpa4: 1qxp A:2-355 [96546]
        Other proteins in same PDB: d1qxpa1, d1qxpa2, d1qxpa3, d1qxpb1, d1qxpb2, d1qxpb3
        mu-like isoform with the large and small subunits fused in a single chain
      2. 2497634Domain d1qxpb4: 1qxp B:2-355 [96550]
        Other proteins in same PDB: d1qxpa1, d1qxpa2, d1qxpa3, d1qxpb1, d1qxpb2, d1qxpb3
        mu-like isoform with the large and small subunits fused in a single chain
    3. Domain for 1tl9:
    4. Domain for 1tlo:
    5. Domain for 2g8e:
    6. Domain for 2g8j:
    7. Domain for 2nqg:
    8. Domain for 2nqi:
    9. Domain for 2r9c:
    10. Domain for 2r9f:

More info for Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II)

Timeline for Protein Calpain large subunit, catalytic domain (domain II) from d.3.1.3: Calpain large subunit, catalytic domain (domain II):