Lineage for d2g8ea1 (2g8e A:33-354)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 715176Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 715177Superfamily d.3.1: Cysteine proteinases [54001] (16 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 715453Family d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)
  6. 715454Protein Calpain large subunit, catalytic domain (domain II) [54041] (5 species)
    includes the N-terminal 'sequence' domain I
  7. 715469Species Rat (Rattus norvegicus), mu-type [TaxId:10116] [75332] (8 PDB entries)
  8. 715477Domain d2g8ea1: 2g8e A:33-354 [134769]
    automatically matched to d1tloa_
    complexed with ca, d5g, mes

Details for d2g8ea1

PDB Entry: 2g8e (more details), 2.25 Å

PDB Description: calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
PDB Compounds: (A:) Calpain-1 catalytic subunit

SCOP Domain Sequences for d2g8ea1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2g8ea1 d.3.1.3 (A:33-354) Calpain large subunit, catalytic domain (domain II) {Rat (Rattus norvegicus), mu-type [TaxId: 10116]}

SCOP Domain Coordinates for d2g8ea1:

Click to download the PDB-style file with coordinates for d2g8ea1.
(The format of our PDB-style files is described here.)

Timeline for d2g8ea1: