SCOPe 2.04: Domain d1zxva3: 1zxv A:264-550

Lineage for d1zxva3 (1zxv A:264-550)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.166: ADP-ribosylation [56398] (1 superfamily)
   unusual fold

4. Superfamily d.166.1: ADP-ribosylation [56399] (8 families)

5. Family d.166.1.1: ADP-ribosylating toxins [56400] (10 proteins)

6. Protein Anthrax toxin lethal factor, middle domain [69845] (1 species)
   includes an all-alpha insert subdomain

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [69846] (9 PDB entries)

8. Domain d1zxva3: 1zxv A:264-550 [125799]
   Other proteins in same PDB: d1zxva1, d1zxva2, d1zxvb1, d1zxvb2
   automated match to d1j7nb3
   complexed with mfm, zn

Details for d1zxva3

PDB Entry: 1zxv, 2.67 Å

PDB Description: X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to a Small Molecule Inhibitor, BI-MFM3, 3-{5-[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionic acid.

PDB Compounds: (A:) Lethal Factor

SCOPe Domain Sequences for d1zxva3:

Sequence, based on SEQRES records:

>d1zxva3 d.166.1.1 (A:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkldi
qpydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmni
nnltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwri
qlspdtragylengklilqrnigleikdvqiikqsekeyiridakvv

Sequence, based on observed residues (ATOM records):

>d1zxva3 d.166.1.1 (A:264-550) Anthrax toxin lethal factor, middle domain {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mlsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriq
idssdflsteekeflkklqidilsekekeflkklkldiqpydinqrlqdtgglidspsin
ldvrkqykrdiqnidallhqsigstlynkiylyenmninnltatlgadlvdstdntkinr
gifnefkknfkysissnymivdinerpaldnerlkwriqlspdtragylengklilqrni
gleikdvqiikqsekeyiridakvv

Timeline for d1zxva3:

• d1zxva3 first appeared in SCOP 1.73
  
• d1zxva3 appears in SCOPe 2.03
  
• d1zxva3 appears in SCOPe 2.05
  
• d1zxva3 appears in the current release, SCOPe 2.08