SCOPe 2.08: Domain d1ya0a1: 1ya0 A:1-497

Lineage for d1ya0a1 (1ya0 A:1-497)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.8: TPR-like [48452] (11 families)

5. Family a.118.8.1: Tetratricopeptide repeat (TPR) [48453] (21 proteins)
   this is a repeat family; one repeat unit is 1zb1 A:166-231 found in domain

6. Protein SMG-7 [140843] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [140844] (1 PDB entry)
   Uniprot Q92540 1-497

8. Domain d1ya0a1: 1ya0 A:1-497 [122785]
   Other proteins in same PDB: d1ya0b_
   complexed with so4
   has additional insertions and/or extensions that are not grouped together

Details for d1ya0a1

PDB Entry: 1ya0, 2.55 Å

PDB Description: Crystal structure of the N-terminal domain of human SMG7

PDB Compounds: (A:) SMG-7 transcript variant 2

SCOPe Domain Sequences for d1ya0a1:

Sequence, based on SEQRES records:

>d1ya0a1 a.118.8.1 (A:1-497) SMG-7 {Human (Homo sapiens) [TaxId: 9606]}
mslqsaqylrqaevlkadmtdsklgpaevwtsrqalqdlyqkmlvtdleyaldkkveqdl
wnhafknqittlqgqaknranpnrsevqanlslfleaasgfytqllqelctvfnvdlpcr
vkssqlgiisnkqthtsaivkpqssscsyicqhclvhlgdiaryrnqtsqaesyyrhaaq
lvpsngqpynqlailasskgdhlttifyycrsiavkfpfpaastnlqkalskalesrdev
ktkwgvsdfikafikfhghvylsksleklsplrekleeqfkellfqkafnsqqlvhvtvi
nlfqlhhlrdfsneteqhtysqdeqlcwtqllalfmsflgilckcplqnesqeesynayp
lpavkvsmdwlrlrprvfqeavvderqyiwpwlisllnsfhpheedlssisatplpeefe
lqgflalrpsfrnldfskghqgitgdkegqqrrirqqrlisigkwiadnqprliqcenev
gkllfiteipeliledp

Sequence, based on observed residues (ATOM records):

>d1ya0a1 a.118.8.1 (A:1-497) SMG-7 {Human (Homo sapiens) [TaxId: 9606]}
mslqsaqylrqaevlkadmtdsklgpaevwtsrqalqdlyqkmlvtdleyaldkkveqdl
wnhafknqittlqgqaknranpnrsevqanlslfleaasgfytqllqelctqssscsyic
qhclvhlgdiaryrnqtsqaesyyrhaaqlvpsngqpynqlailasskgdhlttifyycr
siavkfpfpaastnlqkalskalesrdevktkwgvsdfikafikfhghvylsksleklsp
lrekleeqfkellfqkafnsqqlvhvtvinlfqlhhlrdfsneteqhtysqdeqlcwtql
lalfmsflgilckcplqnsqeesynayplpavkvsmdwlrlrprvfqeavvderqyiwpw
lisllnsfhpheedlsisatplpeefelqgflalrpsfrnldfskghkegqqrrirqqrl
isigkwiadnqprliqcenevgkllfiteipeliledp

Timeline for d1ya0a1:

• d1ya0a1 first appeared in SCOP 1.73
  
• d1ya0a1 appears in SCOPe 2.07