Lineage for Fold a.118: alpha-alpha superhelix

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2332674Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

Superfamilies:

  1. 2332675a.118.1: ARM repeat [48371] (27 families) (S)
  2. 2333420a.118.3: Sec7 domain [48425] (2 families) (S)
  3. 2333475a.118.4: Lipovitellin-phosvitin complex, superhelical domain [48431] (1 family) (S)
  4. 2333480a.118.5: Bacterial muramidases [48435] (1 family) (S)
  5. 2333487a.118.6: Protein prenylyltransferase [48439] (2 families) (S)
  6. 2333633a.118.7: 14-3-3 protein [48445] (1 family) (S)
    automatically mapped to Pfam PF00244
  7. 2333768a.118.8: TPR-like [48452] (10 families) (S)
  8. 2334132a.118.9: ENTH/VHS domain [48464] (5 families) (S)
  9. 2334266a.118.11: Cytochrome c oxidase subunit E [48479] (1 family) (S)
    automatically mapped to Pfam PF02284
  10. 2334344a.118.12: Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain [69099] (1 family) (S)
    automatically mapped to Pfam PF07834
  11. 2334367a.118.13: Arp2/3 complex 16 kDa subunit ARPC5 [69103] (1 family) (S)
    automatically mapped to Pfam PF04699
  12. 2334390a.118.14: FliG [48029] (2 families) (S)
    fragmented superhelix; consist of 3/4-helical motifs and connecting helices
  13. 2334410a.118.15: Aconitase B, N-terminal domain [74778] (1 family) (S)
    automatically mapped to Pfam PF11791
  14. 2334416a.118.16: Translin [74784] (2 families) (S)
    automatically mapped to Pfam PF01997
  15. 2334463a.118.17: Cullin repeat-like [74788] (3 families) (S)
  16. 2334496a.118.18: HCP-like [81901] (1 family) (S)
  17. 2334504a.118.19: C-terminal domain of Ku80 [101420] (1 family) (S)
    automatically mapped to Pfam PF08785
  18. 2334510a.118.20: Hypothetical protein ST1625 [101424] (1 family) (S)
    automatically mapped to Pfam PF09205
  19. 2334515a.118.21: Chemosensory protein Csp2 [100910] (2 families) (S)
    automatically mapped to Pfam PF03392
  20. 2334533a.118.22: IP3 receptor type 1 binding core, domain 2 [100909] (1 family) (S)
    automatically mapped to Pfam PF01365
  21. 2334538a.118.23: USP8 N-terminal domain-like [140856] (1 family) (S)
  22. 2334544a.118.24: Pseudo ankyrin repeat-like [140860] (1 family) (S)
    contains three helices per turn of the superhelix
  23. 2334550a.118.25: TROVE domain-like [140864] (1 family) (S)
    consist of two superhelical sections arranged like a horse-shoe
    automatically mapped to Pfam PF05731
  24. 2334559a.118.26: MgtE N-terminal domain-like [158791] (2 families) (S)
    made of short helices; approximately 2.5 helices per turn of superhelix
    automatically mapped to Pfam PF03448
  25. 2334581a.118.27: DIL domain-like [310601] (1 family) (S)
    Pfam PF01843
  26. 2334625a.118.28: Proteasome regulatory subunit Rpn2 N-terminal domain-like [345915] (1 family) (S)
  27. 2334634a.118.29: U5 small nuclear riboprotein particle assembly factor Aar2 C-terminal domain-like [345916] (1 family) (S)
    C-terminal part of Pfam PF05282
    Structural similarity with VHS domains (48464) noted in PubMed 21764848, but no compelling evidence of homology
  28. 2334647a.118.30: Pre-mRNA splicing factor Prp38 N-terminal-like [345917] (1 family) (S)
    Pfam PF03371
    Structural similarity to HEAT repeats, according to PubMed 26673105
    Some loops between helices form beta hairpins

More info for Fold a.118: alpha-alpha superhelix

Timeline for Fold a.118: alpha-alpha superhelix: