SCOPe 2.08: Domain d1wvga1: 1wvg A:4-358

Lineage for d1wvga1 (1wvg A:4-358)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein CDP-glucose-4,6-dehydratase [102136] (3 species)

7. Species Salmonella typhimurium [TaxId:90371] [141873] (1 PDB entry)
   Uniprot P26397 2-356

8. Domain d1wvga1: 1wvg A:4-358 [121339]
   complexed with apr, cxy
   has additional subdomain(s) that are not in the common domain

Details for d1wvga1

PDB Entry: 1wvg, 1.8 Å

PDB Description: Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi

PDB Compounds: (A:) CDP-glucose 4,6-dehydratase

SCOPe Domain Sequences for d1wvga1:

Sequence, based on SEQRES records:

>d1wvga1 c.2.1.2 (A:4-358) CDP-glucose-4,6-dehydratase {Salmonella typhimurium [TaxId: 90371]}
idknfwqgkrvfvtghtgfkgswlslwltemgaivkgyaldaptvpslfeivrlndlmes
higdirdfeklrssiaefkpeivfhmaaqplvrlsyeqpiktystnvmgtvhlletvkqv
gnikavvnitsdkcydnrewvwgyrenepmggydpysnskgcaelvasafrnsffnpany
eqhgvglasvragnvigggdwakdrlipdilrsfennqqviirnpysirpwqhvleplsg
yivvaqrlytegakfsegwnfgprdedaktvefivdkmvtlwgddaswlldgenhpheah
ylkldcskanmqlgwhprwgltetlsrivkwhkawirgedmlicskreisdymsa

Sequence, based on observed residues (ATOM records):

>d1wvga1 c.2.1.2 (A:4-358) CDP-glucose-4,6-dehydratase {Salmonella typhimurium [TaxId: 90371]}
idknfwqgkrvfvtghtgfkgswlslwltemgaivkgyaldaptvpslfeivrlndlmes
higdirdfeklrssiaefkpeivfhmaaqplvrlsyeqpiktystnvmgtvhlletvkqv
gnikavvnitsdkcydnrewvwgyrenepmggydpysnskgcaelvasafrnsffnpany
eqhgvglasvragnvigggdwakdrlipdilrsfennqqviirnpysirpwqhvleplsg
yivvaqrlytegakfsegwnfgprdedaktvefivdkmvtlwgddaswlldpheahylkl
dcskanmqlgwhprwgltetlsrivkwhkawirgedmlicskreisdymsa

Timeline for d1wvga1:

• d1wvga1 first appeared in SCOP 1.73
  
• d1wvga1 appears in SCOPe 2.07