Lineage for d1t7ja_ (1t7j A:)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2067626Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2067627Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2067628Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2067644Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2067878Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (476 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 2068602Domain d1t7ja_: 1t7j A: [119168]
    automated match to d1k6ca_
    complexed with 478, act

Details for d1t7ja_

PDB Entry: 1t7j (more details), 2.2 Å

PDB Description: crystal structure of inhibitor amprenavir in complex with a multi-drug resistant variant of hiv-1 protease (l63p/v82t/i84v)
PDB Compounds: (A:) Pol polyprotein

SCOPe Domain Sequences for d1t7ja_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1t7ja_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtiriggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qipieicghkaigtvlvgptptnvigrnlltqigctlnf

SCOPe Domain Coordinates for d1t7ja_:

Click to download the PDB-style file with coordinates for d1t7ja_.
(The format of our PDB-style files is described here.)

Timeline for d1t7ja_: