SCOPe 2.02: Domain d1vlca_: 1vlc A:

Lineage for d1vlca_ (1vlc A:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
   the active site is between the two identical subunits

6. Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (10 species)

7. Species Thermotoga maritima [TaxId:2336] [110714] (1 PDB entry)
   Uniprot Q9WZ26

8. Domain d1vlca_: 1vlc A: [108743]
   Structural genomics target
   complexed with cl

Details for d1vlca_

PDB Entry: 1vlc, 1.9 Å

PDB Description: crystal structure of 3-isopropylmalate dehydrogenase (tm0556) from thermotoga maritima at 1.90 a resolution

PDB Compounds: (A:) 3-isopropylmalate dehydrogenase

SCOPe Domain Sequences for d1vlca_:

Sequence; same for both SEQRES and ATOM records:

>d1vlca_ c.77.1.1 (A:) 3-isopropylmalate dehydrogenase, IPMDH {Thermotoga maritima [TaxId: 2336]}
kihhhhhhmkiavlpgdgigpevvrealkvlevvekktgktfekvfghiggdaidrfgep
lpeetkkicleadaiflgsvggpkwddlppekrpeiggllalrkmlnlyanirpikvyrs
lvhvsplkekvigsgvdlvtvrelsygvyygqprgldeekgfdtmiydrktveriartaf
eiaknrrkkvtsvdkanvlyssmlwrkvvnevareypdvelthiyvdnaamqlilkpsqf
dvilttnmfgdilsdesaalpgslgllpsasfgdknlyepaggsapdiagknianpiaqi
lslammlehsfgmveearkieravelvieegyrtrdiaedpekavstsqmgdlickklee
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Timeline for d1vlca_:

• d1vlca_ first appeared in SCOP 1.69
  
• d1vlca_ appears in SCOPe 2.01
  
• d1vlca_ appears in SCOPe 2.03
  
• d1vlca_ appears in the current release, SCOPe 2.08, called d1vlca1