Lineage for Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1182016Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 1182017Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 1182018Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
    the active site is between the two identical subunits

Proteins:

  1. 11820193-isopropylmalate dehydrogenase, IPMDH [53661] (10 species)
    1. 1182020Species Bacillus coagulans [TaxId:1398] [53664] (1 PDB entry)
    2. 1182023Species Chimera (Thermus thermophilus) and (Bacillus subtilis) [TaxId:274] [53663] (2 PDB entries)
    3. 1182026Species Escherichia coli [TaxId:562] [53667] (1 PDB entry)
    4. 1182029Species Mycobacterium tuberculosis [TaxId:1773] [117725] (2 PDB entries)
      Uniprot P95313
    5. 1182038Species Salmonella typhimurium [TaxId:90371] [53666] (1 PDB entry)
    6. 1182041Species Shewanella benthica [TaxId:43661] [195907] (1 PDB entry)
    7. 1182044Species Sulfolobus tokodaii [TaxId:111955] [117724] (1 PDB entry)
      Uniprot P50455
    8. 1182047Species Thermotoga maritima [TaxId:2336] [110714] (1 PDB entry)
      Uniprot Q9WZ26
    9. 1182049Species Thermus thermophilus [TaxId:274] [53662] (14 PDB entries)
    10. 1182072Species Thiobacillus ferrooxidans [TaxId:920] [53665] (1 PDB entry)
  2. 1182075Isocitrate dehydrogenase, ICDH [53668] (2 species)
    1. 1182076Species Bacillus subtilis [TaxId:1423] [64171] (1 PDB entry)
    2. 1182079Species Escherichia coli [TaxId:562] [53669] (26 PDB entries)
  3. 1182106NADP-dependent isocitrate dehydrogenase [82524] (2 species)
    1. 1182107Species Human (Homo sapiens) [TaxId:9606] [110715] (2 PDB entries)
      Uniprot O75874
    2. 1182114Species Pig (Sus scrofa) [TaxId:9823] [82525] (2 PDB entries)
  4. 1182121automated matches [190072] (15 species)
    not a true protein
    1. 1182122Species Acidithiobacillus thiooxidans [TaxId:930] [187607] (1 PDB entry)
    2. 1182127Species Archaeoglobus fulgidus [TaxId:2234] [187335] (1 PDB entry)
    3. 1182130Species Bacillus coagulans [TaxId:1398] [186792] (2 PDB entries)
    4. 1182141Species Burkholderia pseudomallei [TaxId:28450] [188497] (1 PDB entry)
    5. 1182143Species Burkholderia thailandensis [TaxId:271848] [193254] (1 PDB entry)
    6. 1182145Species Campylobacter jejuni [TaxId:197] [189804] (2 PDB entries)
    7. 1182155Species Escherichia coli K-12 [TaxId:83333] [189313] (1 PDB entry)
    8. 1182158Species Escherichia coli [TaxId:562] [193425] (2 PDB entries)
    9. 1182161Species Escherichia coli [TaxId:833333] [194427] (1 PDB entry)
    10. 1182163Species Human (Homo sapiens) [TaxId:9606] [189131] (3 PDB entries)
    11. 1182170Species Mouse (Mus musculus) [TaxId:10090] [187557] (2 PDB entries)
    12. Species Mycobacterium tuberculosis [TaxId:1773] [193947] (1 PDB entry)
    13. 1182177Species Shewanella oneidensis, [TaxId:211586] [194175] (3 PDB entries)
    14. 1182181Species Thermus thermophilus [TaxId:274] [189081] (5 PDB entries)
    15. 1182192Species Thermus thermophilus [TaxId:300852] [192453] (1 PDB entry)

More info for Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

Timeline for Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: