SCOPe 2.08: Domain d1uhlb1: 1uhl B:207-445

Lineage for d1uhlb1 (1uhl B:207-445)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Oxysterols receptor LXR-alpha [109988] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109989] (1 PDB entry)
   Uniprot Q13133 207-445

8. Domain d1uhlb1: 1uhl B:207-445 [107850]
   Other proteins in same PDB: d1uhla_, d1uhlb2
   complexed with 444, mei

Details for d1uhlb1

PDB Entry: 1uhl, 2.9 Å

PDB Description: crystal structure of the lxralfa-rxrbeta lbd heterodimer

PDB Compounds: (B:) Oxysterols receptor LXR-alpha

SCOPe Domain Sequences for d1uhlb1:

Sequence, based on SEQRES records:

>d1uhlb1 a.123.1.1 (B:207-445) Oxysterols receptor LXR-alpha {Human (Homo sapiens) [TaxId: 9606]}
speqlgmieklvaaqqqcnrrsfsdrlrvtpwpmapdphsrearqqrfahftelaivsvq
eivdfakqlpgflqlsredqiallktsaievmlletsrrynpgsesitflkdfsynredf
akaglqvefinpifefsramnelqlndaefalliaisifsadrpnvqdqlqverlqhtyv
ealhayvsihhphdrlmfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdv

Sequence, based on observed residues (ATOM records):

>d1uhlb1 a.123.1.1 (B:207-445) Oxysterols receptor LXR-alpha {Human (Homo sapiens) [TaxId: 9606]}
speqlgmieklvaaqqqcnrrsfearqqrfahftelaivsvqeivdfakqlpgflqlsre
dqiallktsaievmlletsrrynpgsesitdfsynredfakaglqvefinpifefsramn
elqlndaefalliaisifsadrpnvqdqlqverlqhtyvealhayvsihhphdrlmfprm
lmklvslrtlssvhseqvfalrlqdkklppllseiwdv

Timeline for d1uhlb1:

• d1uhlb1 first appeared in SCOP 1.69, called d1uhlb_
  
• d1uhlb1 appears in SCOPe 2.07