SCOPe 2.08: Domain d1sy6l1: 1sy6 L:1-106

Lineage for d1sy6l1 (1sy6 L:1-106)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88528] (43 PDB entries)
   Uniprot P04940 # KV6F_MOUSE IG KAPPA CHAIN V-VI REGION NQ2-17.4.1

8. Domain d1sy6l1: 1sy6 L:1-106 [106115]
   Other proteins in same PDB: d1sy6a1, d1sy6a2, d1sy6h1, d1sy6h2, d1sy6h3, d1sy6l2
   MQ P04940 P01837 # natural chimera

Details for d1sy6l1

PDB Entry: 1sy6, 2.1 Å

PDB Description: crystal structure of cd3gammaepsilon heterodimer in complex with okt3 fab fragment

PDB Compounds: (L:) OKT3 Fab light chain

SCOPe Domain Sequences for d1sy6l1:

Sequence; same for both SEQRES and ATOM records:

>d1sy6l1 b.1.1.1 (L:1-106) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
qivltqspaimsaspgekvtmtcsasssvsymnwyqqksgtspkrwiydtsklasgvpah
frgsgsgtsysltisgmeaedaatyycqqwssnpftfgsgtklein

Timeline for d1sy6l1:

• d1sy6l1 first appeared in SCOP 1.69
  
• d1sy6l1 appears in SCOPe 2.07