Lineage for d1rqdb_ (1rqd B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107257Family c.31.1.1: Deoxyhypusine synthase, DHS [52468] (1 protein)
    automatically mapped to Pfam PF01916
  6. 2107258Protein Deoxyhypusine synthase, DHS [52469] (1 species)
  7. 2107259Species Human (Homo sapiens) [TaxId:9606] [52470] (4 PDB entries)
    Uniprot P49366
  8. 2107265Domain d1rqdb_: 1rqd B: [105060]
    complexed with gc7, nad

Details for d1rqdb_

PDB Entry: 1rqd (more details), 3 Å

PDB Description: deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form with the inhibitor GC7 bound in the active site
PDB Compounds: (B:) deoxyhypusine synthase

SCOPe Domain Sequences for d1rqdb_:

Sequence, based on SEQRES records: (download)

>d1rqdb_ c.31.1.1 (B:) Deoxyhypusine synthase, DHS {Human (Homo sapiens) [TaxId: 9606]}
stqvrgydfnrgvnyralleafgttgfqatnfgravqqvnamiekkleplsqdedqhadl
tqsrrpltsctiflgytsnlissgiretirylvqhnmvdvlvttaggveedlikclapty
lgefslrgkelrenginrignllvpnenyckfedwlmpildqmvmeqntegvkwtpskmi
arlgkeinnpesvyywaqknhipvfspaltdgslgdmiffhsyknpglvldivedlrlin
tqaifakctgmiilgggvvkhhiananlmrngadyavyintaqefdgsdsgarpdeavsw
gkirvdaqpvkvyadaslvfpllvaetfaqkmdafm

Sequence, based on observed residues (ATOM records): (download)

>d1rqdb_ c.31.1.1 (B:) Deoxyhypusine synthase, DHS {Human (Homo sapiens) [TaxId: 9606]}
stqvrgydfnrgvnyralleafgttgfqatnfgravqqvnamiekkleplpltsctiflg
ytsnlissgiretirylvqhnmvdvlvttaggveedlikclaptylgefslrgkelreng
inrignllvpnenyckfedwlmpildqmvmeqntegvkwtpskmiarlgkeinnpesvyy
waqknhipvfspaltdgslgdmiffhsyknpglvldivedlrlintqaifakctgmiilg
ggvvkhhiananlmrngadyavyintaqefdgsdsgarpdeavswgkirvdaqpvkvyad
aslvfpllvaetfaqkmdafm

SCOPe Domain Coordinates for d1rqdb_:

Click to download the PDB-style file with coordinates for d1rqdb_.
(The format of our PDB-style files is described here.)

Timeline for d1rqdb_: