Lineage for Protein: Hydroxyisobutyrate dehydrogenase
- Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds) 
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similarSuperfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) 
Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (19 proteins)
the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
C-terminal domains also show some similarityProtein Hydroxyisobutyrate dehydrogenase [102171] (4 species)
Species:
Pseudomonas aeruginosa [TaxId:208964] [311276] (1 PDB entry) - Domain for 3cum:
Domain d3cuma3: 3cum A:1-162 [305175]
Other proteins in same PDB: d3cuma4
automated match to d3obba2
complexed with act, edo, peg
- Domain for 3cum:
Pseudomonas aeruginosa [TaxId:287] [159424] (2 PDB entries)
Uniprot Q9I5I6 1-162- Domain for 3obb:
Domain d3obba2: 3obb A:1-162 [182915]
Other proteins in same PDB: d3obba1
complexed with act, edo, epe
- Domain for 3q3c:
Domain d3q3ca1: 3q3c A:2-162 [233310]
Other proteins in same PDB: d3q3ca2
automated match to d3obba2
complexed with nad
- Domain for 3obb:
Salmonella typhimurium [TaxId:90371] [110431] (2 PDB entries)
Uniprot Q8ZLV8- Domain for 1tea:
Domain d1teaa3: 1tea A:3-163 [303084]
Other proteins in same PDB: d1teaa4
automated match to d1vpda2
complexed with cl, tar
- Domain for 1vpd:
Domain d1vpda2: 1vpd A:3-163 [113952]
Other proteins in same PDB: d1vpda1
Structural genomics target
complexed with cl, tla
- Domain for 1tea:
Thermus thermophilus [TaxId:274] [102172] (2 PDB entries)
structural genomics- Domains for 1wp4:
Domain d1wp4a2: 1wp4 A:2-157 [121136]
Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
automatically matched to d1j3vc2
complexed with ndp, so4
Domain d1wp4b2: 1wp4 B:2-157 [121138]
Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
automatically matched to d1j3vc2
complexed with ndp, so4
Domain d1wp4c2: 1wp4 C:2-157 [121140]
Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
automatically matched to d1j3vc2
complexed with ndp, so4
Domain d1wp4d2: 1wp4 D:2-157 [121142]
Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
automatically matched to d1j3vc2
complexed with ndp, so4
- Domains for 2cvz:
Domain d2cvza2: 2cvz A:2-157 [130891]
Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
automatically matched to d1j3vc2
complexed with ndp
Domain d2cvzb2: 2cvz B:2-157 [130893]
Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
automatically matched to d1j3vc2
complexed with ndp
Domain d2cvzc2: 2cvz C:2-157 [130895]
Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
automatically matched to d1j3vc2
complexed with ndp
Domain d2cvzd2: 2cvz D:2-157 [130897]
Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
automatically matched to d1j3vc2
complexed with ndp
- Domains for 1wp4:
More info for Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain
Timeline for Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain:
- Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain first appeared in SCOP 1.67
- Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOPe 2.05
- Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOPe 2.07
- Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in the current release, SCOPe 2.08