Lineage for Protein: Hydroxyisobutyrate dehydrogenase

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 387036Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 387037Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families) (S)
  5. 388404Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (13 proteins)
    the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
    C-terminal domains also show some similarity
  6. 388465Protein Hydroxyisobutyrate dehydrogenase [102171] (1 species)

Species:

More info for Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Timeline for Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain:

  • Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain is new in SCOP 1.67
  • Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOP 1.69
  • Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in the current release, SCOPe 2.07