PDB entry 6q91

View 6q91 on RCSB PDB site
Description: Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide
Class: transferase
Keywords: GALK1, fragment, fragment-bound, galactokinase 1, sugar kinase, TRANSFERASE
Deposited on 2018-12-17, released 2019-01-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-23, with a file datestamp of 2019-01-18.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (1-391)
      • expression tag (0)
      • engineered mutation (251-252)
    Domains in SCOPe 2.07: d6q91a1, d6q91a2, d6q91a3
  • Chain 'B':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (1-391)
      • expression tag (0)
      • engineered mutation (251-252)
    Domains in SCOPe 2.07: d6q91b1, d6q91b2, d6q91b3
  • Chain 'C':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (1-391)
      • expression tag (0)
      • engineered mutation (251-252)
    Domains in SCOPe 2.07: d6q91c1, d6q91c2, d6q91c3
  • Chain 'D':
    Compound: Galactokinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GALK1, GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51570 (Start-391)
      • engineered mutation (251-252)
    Domains in SCOPe 2.07: d6q91d1, d6q91d2
  • Heterogens: GAL, HFK, HR8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6q91A (A:)
haalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelm
tvlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaa
plpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagm
pcgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrr
rqceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdy
rafgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasa
aphamrhiqehyggtatfylsqaadgakvlcl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6q91B (B:)
haalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelm
tvlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaa
plpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagm
pcgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrr
rqceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdy
rafgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasa
aphamrhiqehyggtatfylsqaadgakvlcl

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6q91C (C:)
haalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelm
tvlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaa
plpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagm
pcgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrr
rqceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdy
rafgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasa
aphamrhiqehyggtatfylsqaadgakvlcl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6q91D (D:)
haalrqpqvaellaearrafreefgaepelavsapgrvnligehtdynqglvlpmalelm
tvlvgsprkdglvsllttsegadepqrlqfplptaqrslepgtprwanyvkgviqyypaa
plpgfsavvvssvplggglsssaslevatytflqqlcpdsgtiaaraqvcqqaehsfagm
pcgimdqfislmgqkghallidcrsletslvplsdpklavlitnsnvrhslasseypvrr
rqceevaralgaaslrevqleeleaardlvskegfrrarhvvgeirrtaqaaaalrrgdy
rafgrlmveshrslrddyevscpeldqlveaalavpgvygsrmtgggfggctvtlleasa
aphamrhiqehyggtatfylsqaadgakvlcl

    Sequence, based on observed residues (ATOM records): (download) 
    >6q91D (D:)
qvaellaearafreefgaepelavsapgrvnligehtdynqglvlpmalelmtvlvgspd
glvsllttrlqfplptslepgtprwanyvkgviqyypaaplpgfsavvvssvplggglss
saslevatytflqqlcpdsgtiaaraqvcqqaehsmdqfislmgqkghallidcrslets
lvplsdpklavlitnsnvrhsleypvrrrqceevaralgaaslrevqleeleaardlvsk
egfrrarhvvgeirrtaqaaaalrrgdyrafgrlmveshrslrddyevscpeldqlveaa
lavpgvygsrmtgggfggctvtlleasaaphamrhiqehyggtatfylsqaadgakvlcl