PDB entry 4um8

View 4um8 on RCSB PDB site
Description: Crystal structure of alpha V beta 6
Class: immune system
Keywords: immune system, cell surface receptor
Deposited on 2014-05-15, released 2014-11-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-10.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Integrin alpha-V
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06756 (0-End)
      • engineered mutation (399)
    Domains in SCOPe 2.08: d4um8a1, d4um8a2
  • Chain 'B':
    Compound: integrin beta-6
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18564
      • engineered mutation (286)
  • Chain 'C':
    Compound: Integrin alpha-V
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06756 (0-End)
      • engineered mutation (399)
    Domains in SCOPe 2.08: d4um8c1, d4um8c2
  • Chain 'D':
    Compound: integrin beta-6
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18564
      • engineered mutation (286)
  • Heterogens: CL, SO4, NI, CA, CAC, MG, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4um8A (A:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarscppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkqkgairralflysrspshsknmtisrgglmqceelia
ylrdesefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahilldtggle
vlfqgpgenaqlekelqalekenaqlewelqalekelaqttgwrgghvveglageleqlr
arlehhpqgqrepaghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4um8A (A:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarscppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkairralflysrspshsknmtisrgglmqceeliaylr
desefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahill

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4um8C (C:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarscppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkqkgairralflysrspshsknmtisrgglmqceelia
ylrdesefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahilldtggle
vlfqgpgenaqlekelqalekenaqlewelqalekelaqttgwrgghvveglageleqlr
arlehhpqgqrepaghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4um8C (C:)
fnldvdspaeysgpegsyfgfavdffvpssrmfllvgapkanttqpgiveggqvlkcdws
strrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkqer
epvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywqgq
lisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfvsg
vpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplfmd
rgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiaiaa
pyggedkkgivyifngrstglnavpsqilegqwaarscppsfgysmkgatdidkngypdl
ivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclkad
gkgvlprklnfqvellldklkgairralflysrspshsknmtisrgglmqceeliaylrd
esefrdkltpitifmeyrldyrtattglqpilnqftpanisrqahill

  • Chain 'D':
    No sequence available.