PDB entry 4pjx

View 4pjx on RCSB PDB site
Description: Structure of human MR1-Ac-6-FP in complex with human MAIT C-A11 TCR
Class: Immune System
Keywords: MR1, TCR, Immune complex, Ac-6-FP, Immune System
Deposited on 2014-05-12, released 2014-07-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-01, with a file datestamp of 2014-09-26.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.172
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • engineered mutation (261)
    Domains in SCOPe 2.07: d4pjxa1, d4pjxa2, d4pjxa3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d4pjxb1, d4pjxb2
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • engineered mutation (261)
    Domains in SCOPe 2.07: d4pjxc1, d4pjxc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pjxd_
  • Chain 'E':
    Compound: TCR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJX
    Domains in SCOPe 2.07: d4pjxe1, d4pjxe2
  • Chain 'F':
    Compound: TCR-beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJX
    Domains in SCOPe 2.07: d4pjxf1, d4pjxf2
  • Chain 'G':
    Compound: TCR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJX
    Domains in SCOPe 2.07: d4pjxg1, d4pjxg2
  • Chain 'H':
    Compound: TCR-beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJX
    Domains in SCOPe 2.07: d4pjxh1, d4pjxh2
  • Heterogens: 30W, CL, GOL, B3P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pjxA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxA (A:)
mrthslryfrlgvsdpivpefisvgyvdshpittydsvtrqkeprapwmaenlapdhwer
ytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdfli
fnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrtep
plvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqaw
asiellyschvehsgvhmvlqv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pjxB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4pjxC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnralfckahgfyppeiymtwmknidygdilpsgdgtyqawasielnlyschve
hsgvhmvlqv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4pjxD (D:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxD (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4pjxE (E:)
hmgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekg
rfssflsrskgysylllkelqmkdsasylcavrdsnyqliwgagtkliikpdiqnpdpav
yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
dfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxE (E:)
qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
sflsrskgysylllkelqmkdsasylcavrdsnyqliwgagtkliikpdiqnpdpavyql
rdsvclftdfdsqtnvsqskdsdvyitdkcvldmfksnsavawsnksdfacanafnnsii
pedtffp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4pjxF (F:)
hmnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkg
evpngynvsrlnkrefslrlesaapsqtsvyfcassaaveggntiyfgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxF (F:)
gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
gynvsrlnkrefslrlesaapsqtsvyfcassaaveggntiyfgegsrltvledlknvfp
pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
lndsryalssrlrvsatfwqnphfrcqvqfyglsendewtqdrakpvtqivsaeawg

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4pjxG (G:)
hmgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekg
rfssflsrskgysylllkelqmkdsasylcavrdsnyqliwgagtkliikpdiqnpdpav
yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
dfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxG (G:)
qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
sflsrskgysylllkelqmkdsasylcavrdsnyqliwgagtkliikpdiqnpdpavyql
rdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfa
canafnnsiipedtffps

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4pjxH (H:)
hmnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkg
evpngynvsrlnkrefslrlesaapsqtsvyfcassaaveggntiyfgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjxH (H:)
gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
gynvsrlnkrefslrlesaapsqtsvyfcassaaveggntiyfgegsrltvledlknvfp
pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
lndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
a