PDB entry 2wtf

View 2wtf on RCSB PDB site
Description: DNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3-gtg intrastrand cross-link
Class: transferase/DNA
Keywords: transferase-DNA complex, nucleotidyltransferase, translesion DNA synthesis, transferase, DNA-binding, DNA synthesis, DNA replication, mutator protein, DNA damage, DNA repair
Deposited on 2009-09-16, released 2010-03-31
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-08-18, with a file datestamp of 2010-08-13.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.22922
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA Polymerase ETA
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WTF
    • Uniprot Q04049 (23-End)
    Domains in SCOPe 2.04: d2wtfa1, d2wtfa2
  • Chain 'B':
    Compound: DNA Polymerase ETA
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WTF
    • Uniprot Q04049 (23-End)
    Domains in SCOPe 2.04: d2wtfb1, d2wtfb2
  • Chain 'O':
    Compound: 5'-d(*tp*cp*tp*tp*cp*tp*gp*tp*gp*cp *tp*cp*ap*cp*cp*ap*cp)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*tp*gp*gp*tp*gp*ap*gp*cp)-3'
  • Chain 'S':
    Compound: 5'-d(*tp*cp*tp*tp*cp*tp*gp*tp*gp*cp *tp*cp*ap*cp*cp*ap*cp)-3'
  • Chain 'T':
    Compound: 5'-d(*gp*tp*gp*gp*tp*gp*ap*gp*cp)-3'
  • Heterogens: DTP, CA, CPT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wtfA (A:)
maswshpqfekgastslykkagrmskftwkeliqlgspskayesslaciahidmnaffaq
veqmrcglskedpvvcvqwnsiiavsyaarkygisrmdtiqealkkcsnlipihtavfkk
gedfwqyhdgcgswvqdpakqisvedhkvslepyrresrkalkifksacdlverasidev
fldlgricfnmlmfdneyeltgdlklkdalsnireafiggnydinshlplipekikslkf
egdvfnpegrdlitdwddvilalgsqvckgirdsikdilgyttscglsstknvcklasny
kkpdaqtivkndclldfldcgkfeitsfwtlggvlgkelidvldlphensikhiretwpd
nagqlkefldakvkqsdydrstsnidplktadlaeklfklsrgryglplssrpvvksmms
nknlrgkscnsivdciswlevfcaeltsriqdleqeynkiviprtvsislktksyevyrk
sgpvaykginfqshellkvgikfvtdldikgknksyypltklsmtitnfdiidlqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2wtfA (A:)
mskftwkeliqlgspskayesslaciahidmnaffaqveqmrcglskedpvvcvqwnsii
avsyaarkygisrmdtiqealkkcsnlipihtavfkkgedfwqyhdgcgswvqdpakqis
vedhkvslepyrresrkalkifksacdlverasidevfldlgricfnmlmfdneyeltgd
lklkdalsnireafiggnydinshlplipekikslkfegdvfnpegrdlitdwddvilal
gsqvckgirdsikdilgyttscglsstknvcklasnykkpdaqtivkndclldfldcgkf
eitsfwtlggvlgkelidvldlphensikhiretwpdnagqlkefldakvkqsdydrsts
nidplktadlaeklfklsrgryglplssrpvvksmmsnknlrgkscnsivdciswlevfc
aeltsriqdleqeynkiviprtvsislktksyevyrksgpvaykginfqshellkvgikf
vtdldikgknksyypltklsmtitnfdii

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wtfB (B:)
maswshpqfekgastslykkagrmskftwkeliqlgspskayesslaciahidmnaffaq
veqmrcglskedpvvcvqwnsiiavsyaarkygisrmdtiqealkkcsnlipihtavfkk
gedfwqyhdgcgswvqdpakqisvedhkvslepyrresrkalkifksacdlverasidev
fldlgricfnmlmfdneyeltgdlklkdalsnireafiggnydinshlplipekikslkf
egdvfnpegrdlitdwddvilalgsqvckgirdsikdilgyttscglsstknvcklasny
kkpdaqtivkndclldfldcgkfeitsfwtlggvlgkelidvldlphensikhiretwpd
nagqlkefldakvkqsdydrstsnidplktadlaeklfklsrgryglplssrpvvksmms
nknlrgkscnsivdciswlevfcaeltsriqdleqeynkiviprtvsislktksyevyrk
sgpvaykginfqshellkvgikfvtdldikgknksyypltklsmtitnfdiidlqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2wtfB (B:)
mskftwkeliqlgspskayesslaciahidmnaffaqveqmrcglskedpvvcvqwnsii
avsyaarkygisrmdtiqealkkcsnlipihtavfkkgedfwqyhdgcgswvqdpakqis
vedhkvslepyrresrkalkifksacdlverasidevfldlgricfnmlmfdneyeltgd
lklkdalsnireafiggnydinshlplipekikslkfegdvfnpegrdlitdwddvilal
gsqvckgirdsikdilgyttscglsstknvcklasnykkpdaqtivkndclldfldcgkf
eitsfwtlggvlgkelidvldlphensikhiretwpdnagqlkefldakvkqsdydrsts
nidplktadlaeklfklsrgryglplssrpvvksmmsnknlrgkscnsivdciswlevfc
aeltsriqdleqeynkiviprtvsislktksyevyrksgpvaykginfqshellkvgikf
vtdldikgknksyypltklsmtitnfdi

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    No sequence available.