PDB entry 2w4l

View 2w4l on RCSB PDB site
Description: human dcmp deaminase
Class: hydrolase
Keywords: pyrimidine metabolism, nucleotide biosynthesis, zinc, hexamer, hydrolase, metal-binding, phosphoprotein, allosteric enzyme
Deposited on 2008-11-28, released 2009-01-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.202
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxycytidylate deaminase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2w4la_
  • Chain 'B':
    Compound: deoxycytidylate deaminase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2w4lb_
  • Chain 'C':
    Compound: deoxycytidylate deaminase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2w4lc_
  • Chain 'D':
    Compound: deoxycytidylate deaminase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2w4ld_
  • Chain 'E':
    Compound: deoxycytidylate deaminase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W4L
      • conflict (91)
    • Uniprot P32321 (Start-169)
    Domains in SCOPe 2.07: d2w4le_
  • Chain 'F':
    Compound: deoxycytidylate deaminase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2w4lf_
  • Heterogens: ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w4lA (A:)
msckkrddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsdd
vlpwrrtaenkldtkypyvchaelnaimnknltdvkgcsmyvalfpcnecakliiqagik
evifmsdkyhdsdeataarllfnmagvtfrkfipkcskividfdsinsrpsahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2w4lA (A:)
ckkrddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsddvl
pwrrtaenkldtkypyvchaelnaimndvkgcsmyvalfpcnecakliiqagikevifms
dkyhdsdeataarllfnmagvtfrkfipkcskividfdsi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2w4lB (B:)
msckkrddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsdd
vlpwrrtaenkldtkypyvchaelnaimnknltdvkgcsmyvalfpcnecakliiqagik
evifmsdkyhdsdeataarllfnmagvtfrkfipkcskividfdsinsrpsahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2w4lB (B:)
dylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsddvlpwrrt
aenkldtkypyvchaelnaimnkdvkgcsmyvalfpcnecakliiqagikevifmsdkyh
dsdeataarllfnmagvtfrkfipkcskividfdsin

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2w4lC (C:)
msckkrddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsdd
vlpwrrtaenkldtkypyvchaelnaimnknltdvkgcsmyvalfpcnecakliiqagik
evifmsdkyhdsdeataarllfnmagvtfrkfipkcskividfdsinsrpsahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2w4lC (C:)
dylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsddvlppyvc
haelnaimnkvkgcsmyvalfpcnecakliiqagikevifmsdkyhdsdeataarllfnm
agvtfrkfipkcskividfdsi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2w4lD (D:)
msckkrddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsdd
vlpwrrtaenkldtkypyvchaelnaimnknltdvkgcsmyvalfpcnecakliiqagik
evifmsdkyhdsdeataarllfnmagvtfrkfipkcskividfdsinsrpsahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2w4lD (D:)
dylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcvlpwrrtaen
ktkypyvchaelnaimnkvkgcsmyvalfpcnecakliiqagikevifmsdkyhdsdeat
aarllfnmagvtfrkfipkcskividfdsi

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2w4lE (E:)
msckkrddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsdd
vlpwrrtaenkldtkypyvchaelnaimnknltdvkgcsmyvalfpcnecakliiqagik
evifmsdkyhdsdeataarllfnmagvtfrkfipkcskividfdsinsrpsahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2w4lE (E:)
ylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsddvlpwrrta
enkldtkypyvchaelnaimnknltdvkgcsmyvalfpcnecakliiqagikevifmsdk
yhdsdeataarllfnmagvtfrkfipkcskividfdsinsrp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2w4lF (F:)
msckkrddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsdd
vlpwrrtaenkldtkypyvchaelnaimnknltdvkgcsmyvalfpcnecakliiqagik
evifmsdkyhdsdeataarllfnmagvtfrkfipkcskividfdsinsrpsahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2w4lF (F:)
krddylewpeyfmavaflsaqrskdpnsqvgacivnsenkivgigyngmpngcsddvlpw
rrtaenkldtkypyvchaelnaimndvkgcsmyvalfpcnecakliiqagikevifmsdk
yhdsdeataarllfnmagvtfrkfipkcskividfdsin