PDB entry 1t02

View 1t02 on RCSB PDB site
Description: Crystal structure of a Statin bound to class II HMG-CoA reductase
Class: oxidoreductase
Keywords: Statin, HMG-CoA reductase, complex, OXIDOREDUCTASE
Deposited on 2004-04-07, released 2004-08-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-01-21, with a file datestamp of 2015-01-16.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.196
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1t02a1, d1t02a2
  • Chain 'B':
    Compound: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    Species: Pseudomonas mevalonii [TaxId:32044]
    Gene: MVAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1t02b1, d1t02b2
  • Heterogens: SO4, LVA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t02A (A:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >1t02A (A:)
dsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpya
vasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiqd
plnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvrd
amgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsgea
viegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghygs
lttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgla
qnlgamralat

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1t02B (B:)
msldsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfel
pyavasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivg
iqdplnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivd
vrdamgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefs
geaviegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsgh
ygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavav
glaqnlgamralategiqrghmalharniavvagargdevdwvarqlveyhdvradrava
llkqkrgq

    Sequence, based on observed residues (ATOM records): (download) 
    >1t02B (B:)
dsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpya
vasnfqingrdvlvplvveepsivaaasymaklaranggfttsssaplmhaqvqivgiqd
plnarlsllrrkdeiielanrkdqllnslgggcrdievhtfadtprgpmlvahlivdvrd
amgantvntmaeavaplmeaitggqvrlrilsnladlrlaraqvritpqqletaefsgea
viegildayafaavdpyraathnkgimngidplivatgndwraveagahayacrsghygs
lttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqalaeiavavgla
qnlgamralategi