SCOPe 2.08: Domain d1t02a2: 1t02 A:4-110,A:221-374

Lineage for d1t02a2 (1t02 A:4-110,A:221-374)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.179: Substrate-binding domain of HMG-CoA reductase [56541] (1 superfamily)
   unusual fold

4. Superfamily d.179.1: Substrate-binding domain of HMG-CoA reductase [56542] (1 family)

5. Family d.179.1.1: Substrate-binding domain of HMG-CoA reductase [56543] (1 protein)

6. Protein Substrate-binding domain of HMG-CoA reductase [56544] (2 species)

7. Species Pseudomonas mevalonii [TaxId:32044] [56546] (11 PDB entries)
   Uniprot P13702 4-377

8. Domain d1t02a2: 1t02 A:4-110,A:221-374 [106191]
   Other proteins in same PDB: d1t02a1, d1t02b1
   complexed with lva, so4

Details for d1t02a2

PDB Entry: 1t02, 2.6 Å

PDB Description: Crystal structure of a Statin bound to class II HMG-CoA reductase

PDB Compounds: (A:) 3-hydroxy-3-methylglutaryl-coenzyme A reductase

SCOPe Domain Sequences for d1t02a2:

Sequence; same for both SEQRES and ATOM records:

>d1t02a2 d.179.1.1 (A:4-110,A:221-374) Substrate-binding domain of HMG-CoA reductase {Pseudomonas mevalonii [TaxId: 32044]}
dsrlpafrnlspaarldhigqllglshddvsllanagalpmdiangmienvigtfelpya
vasnfqingrdvlvplvveepsivaaasymaklaranggfttsssapXrlaraqvritpq
qletaefsgeaviegildayafaavdpyraathnkgimngidplivatgndwraveagah
ayacrsghygslttwekdnnghlvgtlempmpvglvggatkthplaqlslrilgvktaqa
laeiavavglaqnlgamralat

Timeline for d1t02a2:

• d1t02a2 first appeared in SCOP 1.69
  
• d1t02a2 appears in SCOPe 2.07