SCOPe 2.08: Structural Classification of Proteins

PDB entry 1pzu

View 1pzu on RCSB PDB site
Description: An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site
Class: transcription/DNA
Keywords: TRANSCRIPTION FACTOR, NFAT1-RHR homodimer, PROTEIN-DNA COMPLEX, human IL8 promoter, TRANSCRIPTION/DNA COMPLEX
Deposited on 2003-07-14, released 2003-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.296
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

Chain 'B':
Compound: Nuclear factor of activated T-cells, cytoplasmic 2
Species: Homo sapiens [TaxId:9606]
Gene: NFAT1
Database cross-references and differences (RAF-indexed):
- Uniprot Q13469 (Start-300)
Domains in SCOPe 2.08: d1pzub1, d1pzub2
Chain 'D':
Compound: Nuclear factor of activated T-cells, cytoplasmic 2
Species: Homo sapiens [TaxId:9606]
Gene: NFAT1
Database cross-references and differences (RAF-indexed):
- Uniprot Q13469 (Start-300)
Domains in SCOPe 2.08: d1pzud1, d1pzud2
Chain 'H':
Compound: Nuclear factor of activated T-cells, cytoplasmic 2
Species: Homo sapiens [TaxId:9606]
Gene: NFAT1
Database cross-references and differences (RAF-indexed):
- Uniprot Q13469 (Start-300)
Domains in SCOPe 2.08: d1pzuh1, d1pzuh2
Chain 'I':
Compound: Nuclear factor of activated T-cells, cytoplasmic 2
Species: Homo sapiens [TaxId:9606]
Gene: NFAT1
Database cross-references and differences (RAF-indexed):
- Uniprot Q13469 (Start-300)
Domains in SCOPe 2.08: d1pzui1, d1pzui2
Chain 'L':
Compound: Nuclear factor of activated T-cells, cytoplasmic 2
Species: Homo sapiens [TaxId:9606]
Gene: NFAT1
Database cross-references and differences (RAF-indexed):
- Uniprot Q13469 (Start-300)
Domains in SCOPe 2.08: d1pzul1, d1pzul2
Chain 'M':
Compound: Nuclear factor of activated T-cells, cytoplasmic 2
Species: Homo sapiens [TaxId:9606]
Gene: NFAT1
Database cross-references and differences (RAF-indexed):
- Uniprot Q13469 (Start-300)
Domains in SCOPe 2.08: d1pzum1, d1pzum2
Chain 'T':
Compound: 5'-d(*tp*tp*gp*ap*gp*gp*ap*ap*tp*tp*tp*cp*cp*a)-3'
Chain 'V':
Compound: 5'-d(*tp*tp*gp*ap*gp*gp*ap*ap*tp*tp*tp*cp*cp*a)-3'
Chain 'W':
Compound: 5'-d(*ap*ap*tp*gp*gp*ap*ap*ap*tp*tp*cp*cp*tp*c)-3'
Chain 'X':
Compound: 5'-d(*tp*tp*gp*ap*gp*gp*ap*ap*tp*tp*tp*cp*cp*a)-3'
Chain 'Y':
Compound: 5'-d(*ap*ap*tp*gp*gp*ap*ap*ap*tp*tp*cp*cp*tp*c)-3'
Chain 'Z':
Compound: 5'-d(*ap*ap*tp*gp*gp*ap*ap*ap*tp*tp*cp*cp*tp*c)-3'

PDB Chain Sequences:

Chain 'B':
Sequence, based on SEQRES records: (download)

>1pzuB (B:)
mrgshhhhhhtdphassvplewplssqsgsyelrievqpkphhrahyetegsrgavkapt
gghpvvqlhgymenkplglqifigtaderilkphafyqvhritgktvtttsyekivgntk
vleiplepknnmratidcagilklrnadielrkgetdigrkntrvrlvfrvhipessgri
vslqtasnpiecsqrsahelpmverqdtdsclvyggqqmiltgqnftseskvvftekttd
gqqiwemeatvdkdksqpnmlfveipeyrnkhirtpvkvnfyvingkrkrsqpqhftyhp
v