SCOPe 2.01: Domain d1msma_: 1msm A:

Lineage for d1msma_ (1msm A:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (5 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (378 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d1msma_: 1msm A: [91456]
   complexed with je2; mutant

Details for d1msma_

PDB Entry: 1msm, 2 Å

PDB Description: the hiv protease (mutant q7k l33i l63i) complexed with kni-764 (an inhibitor)

PDB Compounds: (A:) Pol polyprotein

SCOPe Domain Sequences for d1msma_:

Sequence; same for both SEQRES and ATOM records:

>d1msma_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1msma_:

• d1msma_ first appeared in SCOP 1.67
  
• d1msma_ appears in SCOP 1.75
  
• d1msma_ appears in SCOPe 2.02
  
• d1msma_ appears in the current release, SCOPe 2.08