Lineage for d1n8zc2 (1n8z C:323-488)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1353403Fold c.10: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (3 superfamilies)
    2 curved layers, a/b; parallel beta-sheet; order 1234...N; there are sequence similarities between different superfamilies
  4. 1353461Superfamily c.10.2: L domain-like [52058] (9 families) (S)
    less regular structure consisting of variable repeats
  5. 1353531Family c.10.2.5: L domain [52071] (6 proteins)
    this is a repeat family; one repeat unit is 1n8z C:42-66 found in domain
  6. 1353561Protein Protooncoprotein Her2 extracellular domain [82328] (2 species)
  7. 1353562Species Human (Homo sapiens) [TaxId:9606] [82329] (2 PDB entries)
  8. 1353564Domain d1n8zc2: 1n8z C:323-488 [80323]
    Other proteins in same PDB: d1n8za1, d1n8za2, d1n8zb1, d1n8zb2, d1n8zc3, d1n8zc4
    complexed with nag, so4

Details for d1n8zc2

PDB Entry: 1n8z (more details), 2.52 Å

PDB Description: crystal structure of extracellular domain of human her2 complexed with herceptin fab
PDB Compounds: (C:) Receptor protein-tyrosine kinase erbB-2

SCOPe Domain Sequences for d1n8zc2:

Sequence, based on SEQRES records: (download)

>d1n8zc2 c.10.2.5 (C:323-488) Protooncoprotein Her2 extracellular domain {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d1n8zc2 c.10.2.5 (C:323-488) Protooncoprotein Her2 extracellular domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1n8zc2:

Click to download the PDB-style file with coordinates for d1n8zc2.
(The format of our PDB-style files is described here.)

Timeline for d1n8zc2: