SCOPe 2.02: Domain d8icna4: 8icn A:149-335

Lineage for d8icna4 (8icn A:149-335)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (14 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (4 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein DNA polymerase beta, catalytic (31 kD) fragment [81578] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81574] (107 PDB entries)
   Uniprot P06746

8. Domain d8icna4: 8icn A:149-335 [76061]
   Other proteins in same PDB: d8icna1, d8icna3
   protein/DNA complex; complexed with atp, mn, na

Details for d8icna4

PDB Entry: 8icn, 2.8 Å

PDB Description: dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of atp (1 millimolar) and mncl2 (5 millimolar)

PDB Compounds: (A:) protein (DNA polymerase beta (e.c.2.7.7.7))

SCOPe Domain Sequences for d8icna4:

Sequence; same for both SEQRES and ATOM records:

>d8icna4 d.218.1.2 (A:149-335) DNA polymerase beta, catalytic (31 kD) fragment {Human (Homo sapiens) [TaxId: 9606]}
ripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessgdmdvllthpsftsestkqp
kllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndekeyphrridirlipkdqyycg
vlyftgsdifnknmrahalekgftineytirplgvtgvageplpvdsekdifdyiqwkyr
epkdrse

Timeline for d8icna4:

• d8icna4 first appeared in SCOP 1.63
  
• d8icna4 appears in SCOPe 2.01
  
• d8icna4 appears in SCOPe 2.03
  
• d8icna4 appears in the current release, SCOPe 2.08