SCOPe 2.05: Domain d1f42a3: 1f42 A:212-306

Lineage for d1f42a3 (1f42 A:212-306)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.2: Fibronectin type III [49265] (2 families)

5. Family b.1.2.1: Fibronectin type III [49266] (45 proteins)
   Pfam PF00041

6. Protein The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63673] (5 PDB entries)

8. Domain d1f42a3: 1f42 A:212-306 [59638]
   Other proteins in same PDB: d1f42a1
   complexed with mnb

Details for d1f42a3

PDB Entry: 1f42, 2.5 Å

PDB Description: the p40 domain of human interleukin-12

PDB Compounds: (A:) interleukin-12 beta chain

SCOPe Domain Sequences for d1f42a3:

Sequence, based on SEQRES records:

>d1f42a3 b.1.2.1 (A:212-306) The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 {Human (Homo sapiens) [TaxId: 9606]}
kpdppknlqlkplknsrqvevsweypdtwstphsyfsltfcvqvqgkskrekkdrvftdk
tsatvicrknasisvraqdryyssswsewasvpcs

Sequence, based on observed residues (ATOM records):

>d1f42a3 b.1.2.1 (A:212-306) The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 {Human (Homo sapiens) [TaxId: 9606]}
kpdppknlqlkplknsrqvevsweypdtwstphsyfsltfcvqvqgkskrrvftdktsat
vicrknasisvraqdryyssswsewasvpcs

Timeline for d1f42a3:

• d1f42a3 first appeared in SCOP 1.57
  
• d1f42a3 appears in SCOPe 2.04
  
• d1f42a3 appears in SCOPe 2.06
  
• d1f42a3 appears in the current release, SCOPe 2.08