Lineage for Fold g.3: Knottins (small inhibitors, toxins, lectins)

  1. Root: SCOPe 2.04
  2. 1700111Class g: Small proteins [56992] (91 folds)
  3. 1700389Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

Superfamilies:

  1. 1700390g.3.1: Plant lectins/antimicrobial peptides [57016] (3 families) (S)
  2. 1700571g.3.2: Plant inhibitors of proteinases and amylases [57027] (1 family) (S)
  3. 1700628g.3.3: Cyclotides [57038] (4 families) (S)
    macrocyclic plant knottins closed with the formation of an Asn-Gly peptide
  4. 1700676g.3.4: Gurmarin-like [57048] (2 families) (S)
  5. 1700689g.3.5: Agouti-related protein [57055] (1 family) (S)
    automatically mapped to Pfam PF05039
  6. 1700695g.3.6: omega toxin-like [57059] (5 families) (S)
  7. 1700854g.3.7: Scorpion toxin-like [57095] (5 families) (S)
  8. 1701209g.3.8: Cellulose-binding domain [57180] (1 family) (S)
  9. 1701219g.3.9: Growth factor receptor domain [57184] (2 families) (S)
  10. 1701300g.3.10: Colipase-like [57190] (1 family) (S)
  11. 1701322g.3.11: EGF/Laminin [57196] (8 families) (S)
  12. 1701948g.3.12: Bromelain inhibitor VI (cysteine protease inhibitor) [57243] (1 family) (S)
  13. 1701956g.3.13: Bowman-Birk inhibitor, BBI [57247] (2 families) (S)
  14. 1702002g.3.14: Elafin-like [57256] (2 families) (S)
    automatically mapped to Pfam PF00095
  15. 1702015g.3.15: Leech antihemostatic proteins [57262] (3 families) (S)
  16. 1702065g.3.16: Granulin repeat [57277] (1 family) (S)
  17. 1702077g.3.17: Satiety factor CART (cocaine and amphetamine regulated transcript) [64546] (1 family) (S)
    automatically mapped to Pfam PF06373
  18. 1702082g.3.18: DPY module [90148] (1 family) (S)
  19. 1702087g.3.19: Bubble protein [103565] (1 family) (S)
    automatically mapped to Pfam PF09227

More info for Fold g.3: Knottins (small inhibitors, toxins, lectins)

Timeline for Fold g.3: Knottins (small inhibitors, toxins, lectins):