SCOPe 2.06: Family a.138.1.1: Cytochrome c3-like

Lineage for Family a.138.1.1: Cytochrome c3-like

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.138: Multiheme cytochromes [48694] (1 superfamily)
   variable number of helices and little beta structure; not a true fold

4. Superfamily a.138.1: Multiheme cytochromes [48695] (4 families)
   duplication: contains multiple CxxCH motifs

5. Family a.138.1.1: Cytochrome c3-like [48696] (5 proteins)

Proteins:

1. 16-heme cytochrome c HmcA [81940] (1 species)
   tandem repeat of four cytochrome c3-like domains

   • Species Desulfovibrio vulgaris [TaxId:881] [81941] (3 PDB entries)

2. Cytochrome c3 [48697] (7 species)
   contains four heme groups

   1. Species Desulfomicrobium norvegicum [TaxId:52561] [48702] (1 PDB entry)
      synonym: Desulfovibrio desulfuricans Norway

   2. Species Desulfovibrio africanus [TaxId:873] [48701] (2 PDB entries)

   3. Species Desulfovibrio baculatus (Desulfomicrobium baculatus) [TaxId:899] [117036] (1 PDB entry)
      Uniprot Q6XCI5 # fragment

   4. Species Desulfovibrio desulfuricans, different strains [TaxId:876] [48698] (10 PDB entries)
      Uniprot Q9L915

   5. Species Desulfovibrio gigas [TaxId:879] [48700] (3 PDB entries)

   6. Species Desulfovibrio gigas, di-tetraheme cytochrome c3 [TaxId:879] [74804] (1 PDB entry)
      disulfide-crosslinked dimer

   7. Species Desulfovibrio vulgaris [TaxId:881] [48699] (18 PDB entries)
      Uniprot P00132

3. Cytochrome c7 (cytochrome c551.5, PpcA) [48703] (3 species)
   contains three heme groups; deletion of one of Cyt c3 heme-binding sites

   1. Species Desulfuromonas acetoxidans [TaxId:891] [48704] (8 PDB entries)

   2. Species Geobacter sulfurreducens, GSU1996 [TaxId:35554] [110039] (1 PDB entry)
      Uniprot Q74BP5

   3. Species Geobacter sulfurreducens, PpcA [TaxId:35554] [101502] (3 PDB entries)

4. Nine-heme cytochrome c [48705] (2 species)
   tandem repeat of two cytochrome c3-like domains with additional heme-binding site in the domain interface

   1. Species Desulfovibrio desulfuricans, ATCC 27774 [TaxId:876] [48706] (3 PDB entries)

   2. Species Desulfovibrio desulfuricans, ATCC 29577 [TaxId:876] [63634] (1 PDB entry)

5. automated matches [190934] (3 species)
   not a true protein

   1. Species Desulfovibrio vulgaris [TaxId:883] [255134] (1 PDB entry)

   2. Species Geobacter sulfurreducens [188477] (1 PDB entry)

   3. Species Geobacter sulfurreducens [TaxId:35554] [189147] (16 PDB entries)

More info for Family a.138.1.1: Cytochrome c3-like

Timeline for Family a.138.1.1: Cytochrome c3-like:

• Family a.138.1.1: Cytochrome c3-like first appeared (with stable ids) in SCOP 1.55
  
• Family a.138.1.1: Cytochrome c3-like appears in SCOPe 2.05
  
• Family a.138.1.1: Cytochrome c3-like appears in SCOPe 2.07
  
• Family a.138.1.1: Cytochrome c3-like appears in the current release, SCOPe 2.08