SCOPe 2.08: Family a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators)

Lineage for Family a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.6: C-terminal effector domain of the bipartite response regulators [46894] (4 families)
   binds to DNA and RNA polymerase; the N-terminal, receiver domain belongs to the CheY family

5. Family a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators) [46900] (5 proteins)
   contains additional, fourth helix in the C-terminal extension

Proteins:

1. Germination protein GerE [63488] (1 species)
   single-domain protein homologous to the C-terminal domain of NarL

   • Species Bacillus subtilis [TaxId:1423] [63489] (1 PDB entry)

2. Nitrate/nitrite response regulator (NarL) [46901] (1 species)

   • Species Escherichia coli [TaxId:562] [46902] (5 PDB entries)

3. Quorum-sensing transcription factor TraR, C-terminal domain [74690] (1 species)

   • Species Agrobacterium tumefaciens [TaxId:358] [74691] (2 PDB entries)

4. Response regulatory protein StyR, C-terminal domain [140317] (1 species)

   • Species Pseudomonas fluorescens [TaxId:294] [140318] (2 PDB entries)
     Uniprot O30989 131-200

5. Transcriptional regulator RcsB [88990] (1 species)

   • Species Erwinia amylovora [TaxId:552] [88991] (1 PDB entry)

More info for Family a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators)

Timeline for Family a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators):

• Family a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators) first appeared (with stable ids) in SCOP 1.55, called Family a.4.6.2: Nitrate/nitrite response regulator (NARL)
  
• Family a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators) appears in SCOPe 2.07