SCOPe 2.02: Domain d3htci_: 3htc I:

Lineage for d3htci_ (3htc I:)

1. Root: SCOPe 2.02

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.15: Leech antihemostatic proteins [57262] (3 families)

5. Family g.3.15.2: Hirudin-like [57270] (4 proteins)

6. Protein Hirudin [57271] (1 species)

7. Species Medicinal leech (Hirudo medicinalis) [TaxId:6421] [57272] (8 PDB entries)

8. Domain d3htci_: 3htc I: [44369]
   Other proteins in same PDB: d3htc.1
   CA-atoms only

Details for d3htci_

PDB Entry: 3htc, 2.3 Å

PDB Description: the structure of a complex of recombinant hirudin and human alpha-thrombin

PDB Compounds: (I:) hirudin variant 2

SCOPe Domain Sequences for d3htci_:

Sequence; same for both SEQRES and ATOM records:

>d3htci_ g.3.15.2 (I:) Hirudin {Medicinal leech (Hirudo medicinalis) [TaxId: 6421]}
itytdctesgqnlclcegsnvcgkgnkcilgsngkgnqcvtgegtpkpeshnngdfeeip
eeylq

Timeline for d3htci_:

• d3htci_ first appeared (with stable ids) in SCOP 1.55
  
• d3htci_ appears in SCOPe 2.01
  
• d3htci_ appears in SCOPe 2.03
  
• d3htci_ appears in the current release, SCOPe 2.08