SCOPe 2.05: Domain d3mdeb2: 3mde B:11-241

Lineage for d3mdeb2 (3mde B:11-241)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.6: Acyl-CoA dehydrogenase NM domain-like [56644] (1 superfamily)
   2 domains: (1) all-alpha: 5 helices; (2) contains an open beta-sheet barrel: n*=5, S*=8; complex topology

4. Superfamily e.6.1: Acyl-CoA dehydrogenase NM domain-like [56645] (3 families)
   flavoprotein: binds FAD; constituent families differ in the numbers of C-terminal domains (four-helical bundles)

5. Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains [56646] (10 proteins)

6. Protein Medium chain acyl-CoA dehydrogenase, NM domains [56649] (3 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [56650] (3 PDB entries)

8. Domain d3mdeb2: 3mde B:11-241 [42856]
   Other proteins in same PDB: d3mdea1, d3mdeb1
   complexed with co8, fad

Details for d3mdeb2

PDB Entry: 3mde, 2.4 Å

PDB Description: crystal structures of medium chain acyl-coa dehydrogenase from pig liver mitochondria with and without substrate

PDB Compounds: (B:) medium chain acyl-coa dehydrogenase

SCOPe Domain Sequences for d3mdeb2:

Sequence; same for both SEQRES and ATOM records:

>d3mdeb2 e.6.1.1 (B:11-241) Medium chain acyl-CoA dehydrogenase, NM domains {Pig (Sus scrofa) [TaxId: 9823]}
gfsfelteqqkefqatarkfareeiipvaaeydrtgeypvpllkrawelglmnthipesf
gglglgiidscliteelaygctgvqtaieantlgqvpliiggnyqqqkkylgrmteeplm
caycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyfllarsdpdpkapa
skaftgfiveadtpgvqigrkeinmgqrcsdtrgivfedvrvpkenvltge

Timeline for d3mdeb2:

• d3mdeb2 first appeared (with stable ids) in SCOP 1.55
  
• d3mdeb2 appears in SCOPe 2.04
  
• d3mdeb2 appears in SCOPe 2.06
  
• d3mdeb2 appears in the current release, SCOPe 2.08