SCOP 1.75: Domain d1f3md_: 1f3m D:

Lineage for d1f3md_ (1f3m D:)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein pak1 [56146] (1 species)
   OPK group; PAK/STE20 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56147] (2 PDB entries)

8. Domain d1f3md_: 1f3m D: [41678]
   Other proteins in same PDB: d1f3ma_, d1f3mb_
   complexed with iod; mutant

Details for d1f3md_

PDB Entry: 1f3m, 2.3 Å

PDB Description: crystal structure of human serine/threonine kinase pak1

PDB Compounds: (D:) serine/threonine-protein kinase pak-alpha

SCOP Domain Sequences for d1f3md_:

Sequence, based on SEQRES records:

>d1f3md_ d.144.1.7 (D:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtp
ywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpe
klsaifrdflnrcldmdvekrgsakellqhqflkiakplssltpliaaakeatk

Sequence, based on observed residues (ATOM records):

>d1f3md_ d.144.1.7 (D:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpgtpywmapevvt
rkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdf
lnrcldmdvekrgsakellqhqflkiakplssltpliaaakeatk

Timeline for d1f3md_:

• d1f3md_ first appeared (with stable ids) in SCOP 1.55
  
• d1f3md_ appears in SCOP 1.73
  
• d1f3md_ appears in SCOPe 2.01
  
• d1f3md_ appears in the current release, SCOPe 2.08