SCOPe 2.05: Domain d1f4fa_: 1f4f A:

Lineage for d1f4fa_ (1f4f A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (64 PDB entries)

8. Domain d1f4fa_: 1f4f A: [40946]
   complexed with so4, tp3

Details for d1f4fa_

PDB Entry: 1f4f, 2 Å

PDB Description: crystal structure of e. coli thymidylate synthase complexed with sp- 722

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d1f4fa_:

Sequence; same for both SEQRES and ATOM records:

>d1f4fa_ d.117.1.1 (A:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapv

Timeline for d1f4fa_:

• d1f4fa_ first appeared (with stable ids) in SCOP 1.55
  
• d1f4fa_ appears in SCOPe 2.04
  
• d1f4fa_ appears in SCOPe 2.06
  
• d1f4fa_ appears in the current release, SCOPe 2.08