SCOPe 2.07: Domain d6w4gb1: 6w4g B:2-562

Lineage for d6w4gb1 (6w4g B:2-562)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus genotype 1b (isolate bk) [TaxId:11105] [188687] (17 PDB entries)

8. Domain d6w4gb1: 6w4g B:2-562 [396061]
   Other proteins in same PDB: d6w4ga2, d6w4gb2
   automated match to d2ax0a_
   complexed with sl4

Details for d6w4gb1

PDB Entry: 6w4g, 1.95 Å

PDB Description: hepatitis c virus polymerase ns5b with ro inhibitor for sar studies

PDB Compounds: (B:) NS5b

SCOPe Domain Sequences for d6w4gb1:

Sequence, based on SEQRES records:

>d6w4gb1 e.8.1.4 (B:2-562) automated matches {Hepatitis C virus genotype 1b (isolate bk) [TaxId: 11105]}
msytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihs
vwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvst
lpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyq
ccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasa
acraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydle
litscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwa
rmilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspge
inrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipa
asrldlsgwfvagysggdiyh

Sequence, based on observed residues (ATOM records):

>d6w4gb1 e.8.1.4 (B:2-562) automated matches {Hepatitis C virus genotype 1b (isolate bk) [TaxId: 11105]}
msytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihs
vwkdlledtvtpidttimaknevfcvqrkparlivfpdlgvrvcekmalydvvstlpqvv
mgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccdla
pearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacraa
klqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydlelitsc
ssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmilm
thffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinrva
sclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpiwfvagys
ggdiyh

Timeline for d6w4gb1:

• d6w4gb1 is new in SCOPe 2.07-stable
  
• d6w4gb1 appears in the current release, SCOPe 2.08