SCOPe 2.07: Domain d6fugc1: 6fug C:16-243

Lineage for d6fugc1 (6fug C:16-243)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Factor D [50563] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50564] (24 PDB entries)

8. Domain d6fugc1: 6fug C:16-243 [353207]
   Other proteins in same PDB: d6fuga2, d6fugc2, d6fugd2, d6fuge2, d6fugf2
   automated match to d1bioa_
   complexed with e85

Details for d6fugc1

PDB Entry: 6fug, 2.21 Å

PDB Description: complement factor d in complex with the inhibitor 3-((3-((3- (aminomethyl)phenyl)amino)-1h-pyrazolo[3,4-d]pyrimidin-4-yl)amino) phenol

PDB Compounds: (C:) complement factor d

SCOPe Domain Sequences for d6fugc1:

Sequence, based on SEQRES records:

>d6fugc1 b.47.1.2 (C:16-243) Factor D {Human (Homo sapiens) [TaxId: 9606]}
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahcledaadgkvqvllgahsl
sqpepskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapg
tlcdvagwgivnhagrrpdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsck
gdsggplvcggvlegvvtsgsrvcgnrkkpgiytrvasyaawidsvla

Sequence, based on observed residues (ATOM records):

>d6fugc1 b.47.1.2 (C:16-243) Factor D {Human (Homo sapiens) [TaxId: 9606]}
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahclegkvqvllgahslsqpe
pskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapgtlcd
vagwgivnhagrrpdslqhvllpvldratcnrraiterlmcaesnrrdsckgdsggplvc
ggvlegvvtrvcgnrkkpgiytrvasyaawidsvla

Timeline for d6fugc1:

• d6fugc1 is new in SCOPe 2.07-stable
  
• d6fugc1 appears in the current release, SCOPe 2.08