SCOPe 2.07: Domain d4zh1b_: 4zh1 B:

Lineage for d4zh1b_ (4zh1 B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families)

5. Family a.102.4.4: Complement components [48251] (4 proteins)
   probably related to other families, but has no known enzymatic activity

6. Protein Thio-ester containing domain (TED) from Complement C3, aka C3d or C3dg [48252] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48253] (19 PDB entries)

8. Domain d4zh1b_: 4zh1 B: [280571]
   Other proteins in same PDB: d4zh1a2
   automated match to d1ghqa_
   complexed with bgc, gal, gol, nga, sia

Details for d4zh1b_

PDB Entry: 4zh1, 2.24 Å

PDB Description: complement factor h in complex with the gm1 glycan

PDB Compounds: (B:) Complement C3

SCOPe Domain Sequences for d4zh1b_:

Sequence, based on SEQRES records:

>d4zh1b_ a.102.4.4 (B:) Thio-ester containing domain (TED) from Complement C3, aka C3d or C3dg {Human (Homo sapiens) [TaxId: 9606]}
vtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgytqqlafrqpss
afaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqkpdgvfqedapv
ihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkagdfleanymnlq
rsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveatsyallallqlk
dfdfvppvvrwlneqryygggygstqatfmvfqalaqyqkdapdhqelnldvslqlp

Sequence, based on observed residues (ATOM records):

>d4zh1b_ a.102.4.4 (B:) Thio-ester containing domain (TED) from Complement C3, aka C3d or C3dg {Human (Homo sapiens) [TaxId: 9606]}
vtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgytqqlafrqpss
afaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqkpdgvfqedapv
ihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkagdfleanymnlq
rsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveatsyallallqlk
dfdfvppvvrwlneqrygstqatfmvfqalaqyqkdapdhqelnldvslqlp

Timeline for d4zh1b_:

• d4zh1b_ first appeared in SCOPe 2.05
  
• d4zh1b_ appears in SCOPe 2.06
  
• d4zh1b_ appears in the current release, SCOPe 2.08