SCOPe 2.05: Domain d4isyc_: 4isy C:

Lineage for d4isyc_ (4isy C:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families)

5. Family c.67.1.0: automated matches [191328] (1 protein)
   not a true family

6. Protein automated matches [190151] (98 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:1773] [225404] (19 PDB entries)

8. Domain d4isyc_: 4isy C: [266466]
   automated match to d4r5fa_
   complexed with gol, so4

Details for d4isyc_

PDB Entry: 4isy, 2.59 Å

PDB Description: Crystal structure of IscS from Mycobacterium tuberculosis

PDB Compounds: (C:) Cysteine desulfurase

SCOPe Domain Sequences for d4isyc_:

Sequence, based on SEQRES records:

>d4isyc_ c.67.1.0 (C:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
sayldhaattpmhpaaieamaavqrtignasslhtsgrsarrrieeareliadklgarps
eviftaggtesdnlavkgiywarrdaephrrrivttevehhavldsvnwlvehegahvtw
lptaadgsvsatalrealqshddvalvsvmwannevgtilpiaemsvvamefgvpmhsda
iqavgqlpldfgasglsamsvaghkfggppgvgalllrrdvtcvplmhgggqerdirsgt
pdvasavgmataaqiavdgleensarlrllrdrlvegvlaeiddvclngaddpmrlagna
hftfrgcegdallmlldangiecstgsactagvaqpshvliamgvdaasargslrlslgh
tsveadvdaalevlpgavararraalaaag

Sequence, based on observed residues (ATOM records):

>d4isyc_ c.67.1.0 (C:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
sayldhaattpmhpaaieamaavqrtignasslhtsgrsarrrieeareliadklgarps
eviftaggtesdnlavkgiywarrdaephrrrivttevehhavldsvnwlvehegahvtw
lptaadgsvsatalrealqshddvalvsvmwannevgtilpiaemsvvamefgvpmhsda
iqavgqlpldfgasglsamsvaghkfggppgvgalllrrdvtcvplmhgggqerdirsgt
pdvasavgmataaqiavdgleensarlrllrdrlvegvlaeiddvclngaddpmrlagna
hftfrgcegdallmlldangiecstgsapshvliamgvdaasargslrlslghtsveadv
daalevlpgavararraalaaag

Timeline for d4isyc_:

• d4isyc_ is new in SCOPe 2.05-stable
  
• d4isyc_ is called d4isyc1 in SCOPe 2.06
  
• d4isyc_ appears in the current release, SCOPe 2.08, called d4isyc1