SCOPe 2.07: Domain d4tlra_: 4tlr A:

Lineage for d4tlra_ (4tlr A:)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus (isolate 1) [TaxId:11104] [261697] (1 PDB entry)

8. Domain d4tlra_: 4tlr A: [261698]
   automated match to d3gnwb_
   complexed with 33h, 79z

Details for d4tlra_

PDB Entry: 4tlr, 1.86 Å

PDB Description: ns5b in complex with lactam-thiophene carboxylic acids

PDB Compounds: (A:) NS5b

SCOPe Domain Sequences for d4tlra_:

Sequence; same for both SEQRES and ATOM records:

>d4tlra_ e.8.1.4 (A:) automated matches {Hepatitis C virus (isolate 1) [TaxId: 11104]}
smsytwtgalitpcaaeetklpinalsnsllrhhnlvyattsrsaslrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsarskfgygakdvrnlsskavnhir
svwkdlledtetpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqavmgssygfqyspgqrveflvnawkakkcpmgfaydtrcfdstvtendirveesiy
qccdlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkaa
aacraaklqdctmlvcgddlvvicesagtqedeaslrafteamtrysappgdppkpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiiqrlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavrtklkltpip
aasqldlsswfvagysggdiyhsl

Timeline for d4tlra_:

• d4tlra_ first appeared in SCOPe 2.04
  
• d4tlra_ appears in SCOPe 2.06
  
• d4tlra_ appears in the current release, SCOPe 2.08